Recruiting NCT05729932
Cannabis and Opioid Use Disorder
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Inhaled vaporized cannabis, Intransal opioid.
- Who it may be relevant to
- Registry conditions: Opioid Use Disorder. Basic parameters: 18 years — 55 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Cannabis Modulation of Outcomes Related to Opioid Use Disorder: Opioid Withdrawal, Abuse Potential and Safety
Overview
This study plans to enroll participants with opioid use disorder who are not currently seeking treatment to assess the effects of cannabis on opioid withdrawal and other related outcomes.
Interventions
- Drug Inhaled vaporized cannabis
Double-blind cannabis and placebo doses, administered through vaporizer - Drug Intransal opioid
Double-blind opioid and placebo doses, administered intranasal route
Primary outcome measures
- Change from Baseline - Opioid Withdrawal Severity - Visual Analog Scale (VAS) [Time frame: Change from baseline]
Secondary outcome measures (2)
- Change from Baseline - Opioid Drug Liking - Visual Analog Scale (VAS) [Time frame: Change from baseline]
- Change from Baseline - Respiration [Time frame: Change from baseline]
Eligibility criteria
Inclusion criteria
- Current opioid use disorder
Exclusion criteria
- Current medical conditions that require medical management
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Crossover
- Masking
- Triple blind
- Primary purpose
- Basic science
Study locations
United States · 1 center
- Center on Drug and Alcohol Research — Lexington
Identifiers
NCT: NCT05729932 · 75562-20242 · 1R01DA054347