Menu
Recruiting NCT05706532

Cardiovascular and Cerebrovascular Control in Healthy Subjects

— Observational Healthy Autonomic Nervous System Cerebral Autoregulation

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: active standing.
Who it may be relevant to
Registry conditions: Healthy, Autonomic Nervous System, Cerebral Autoregulation. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Italy
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Cardiovascular and Cerebrovascular Control in Healthy Adult Subjects

Overview

The aim of the study is to evaluate autonomic function and cerebrovascular control in 60 healthy subjects by means of noninvasive analysis of time series variability. To this extent, heart period, systolic and mean arterial blood pressure, cerebral blood velocity, peripheral resistances, respiration will be recorded from subjects during an orthostatic challenge. The interactions between autonomic cardiovascular function, cerebrovascular and peripheral control will be evaluated exploiting the most advanced signal processing techniques.

Interventions

  • Diagnostic test active standing
    Data are acquired with patients resting in supine position for 10 minutes and for 10 minutes during active standing

Primary outcome measures

  • Evaluate the state and interactions of autonomic function and cerebrovascular control [Time frame: 12 months]

Eligibility criteria

Inclusion criteria

  • age >18
  • sinus rhythm
  • informed consent signed

Exclusion criteria

  • age <18
  • presence of autonomic nervous system diseases or dysfunctions

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Cohort

Study locations

Italy · 1 center
  • IRCCS Policlinico San Donato — San Donato Milanese

Identifiers

NCT: NCT05706532 · CardioSan

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗