Menu
Recruiting NCT05701579

Assessment of Anterior Cruciate Ligament (ACL) Degeneratio Mucosa Treatment

— Observational Anterior Cruciate Ligament Injuries

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: ACL "decompression".
Who it may be relevant to
Registry conditions: Anterior Cruciate Ligament Injuries. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Poland
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

Anterior Cruciate Ligament (ACL) Degeneratio Mucosa is a condition resulting from mucoid degeneration of ACL. Exact etiology is unknown, however ACL Degeneratio Mucosa impairs everyday functioning. In the literature there were some reports of treatment by ACL excision and subsequent reconstruction, however such treatment brings risk of deteriorated function. In this study the investigator will evaluate the technique of ACL "decompression" by the means of longitudinal incisions and evacuation of extrafibrous mucoid tissue.

Interventions

  • Procedure ACL "decompression"
    The technique of ACL "decompression" by the means of longitudinal incisions and evacuation of extrafibrous mucoid tissue.

Primary outcome measures

  • Range of motion [Time frame: At the 12 month of the follow-up]
  • Range of motion [Time frame: At the 24 month of the follow-up]
  • Knee anterior translatory stability [Time frame: At the 12 month of the follow-up]
  • Knee anterior translatory stability [Time frame: At the 24 month of the follow-up]
  • Knee anterolateral rotational stability [Time frame: At the 24 month of the follow-up]
Secondary outcome measures (4)
  • The functional assessment with the The International Knee Documentation Committee Questionnaire (IKDC) [Time frame: At the 12 month of the follow-up]
  • The functional assessment with the The International Knee Documentation Committee Questionnaire (IKDC) [Time frame: At the 24 month of the follow-up]
  • The functional assessment with the Knee injury and Osteoarthritis Outcome Score (KOOS) [Time frame: At the 12 month of the follow-up]
  • The functional assessment with the Knee injury and Osteoarthritis Outcome Score (KOOS) [Time frame: At the 24 month of the follow-up]

Eligibility criteria

Inclusion criteria

  • patients with ACL degeneratio mucosa decided to undergo a surgical treatment
  • range of motion impairment caused by mucoid or cystic changes in ACL confirmed by MRI

Exclusion criteria

  • non-adherence to the study protocol
  • active knee inflammation
  • range of motion impairment due to other extra- and intra-articular reasons

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Poland · 1 center
  • Artromedical Orthopaedic Clinic — Bełchatów

Publications

  • Gersing AS, Schwaiger BJ, Nevitt MC, Joseph GB, Feuerriegel G, Jungmann PM, Guimaraes JB, Facchetti L, McCulloch CE, Makowski MR, Link TM. Anterior cruciate ligament abnormalities are associated with accelerated progression of knee joint degeneration in knees with and without structural knee joint abnormalities: 96-month data from the Osteoarthritis Initiative. Osteoarthritis Cartilage. 2021 Jul;2 PMID 33775919
  • Lintz F, Pujol N, Boisrenoult P, Bargoin K, Beaufils P, Dejour D. Anterior cruciate ligament mucoid degeneration: a review of the literature and management guidelines. Knee Surg Sports Traumatol Arthrosc. 2011 Aug;19(8):1326-33. doi: 10.1007/s00167-011-1433-0. Epub 2011 Feb 18. PMID 21331652
  • Sweed T, Mussa M, El-Bakoury A, Geutjens G, Metcalfe A. Management of mucoid degeneration of the anterior cruciate ligament: a systematic review. Knee Surg Relat Res. 2021 Aug 21;33(1):26. doi: 10.1186/s43019-021-00110-6. PMID 34419162
  • Lee JW, Ahn JT, Gwak HG, Lee SH. Clinical Outcomes of Arthroscopic Notchplasty and Partial Resection for Mucoid Degeneration of the Anterior Cruciate Ligament. J Clin Med. 2021 Jan 16;10(2):315. doi: 10.3390/jcm10020315. PMID 33467062

Identifiers

NCT: NCT05701579 · 1-pro-ar-2023

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗