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Recruiting NCT05614193

Deep Enhanced Imaging in Stroke and Vascular Neurology

Observational Radiology Cerebral Stroke Vascular Diseases

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Deep learning imaging enhancement.
Who it may be relevant to
Registry conditions: Radiology, Cerebral Stroke, Vascular Diseases. Basic parameters: 18 years — 100 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

To investigate the performance of enhanced computed tomography (CT) or magnetic resonance (MR) imaging by deep learning relative to conventional CT or MR imaging in brain stroke and vascular neurology. We expect that the deep enhanced imaging method can shorten the time stay in the imaging session of stroke patients, optimize the overall imaging quality and improve the patients' care in imaging session.

Detailed description

Early diagnosis of cerebral infarction, detection of ischemic penumbra, evaluation of collateral circulation and identification of vascular lesions by imaging are critical for treatment decision and outcome improvement in cerebral stroke. Multimodal computed tomography (CT) and magnetic resonance (MR) imaging are most prevalent and accessible approaches in clinical scenarios. These two approaches are downgraded either by radiation exposure or long scanning time which may hinder the rapid treatment for patients. Deep learning has shown substantial achievements in medical imaging enhancement. The added value of deep learning method in stroke and vascular neurology has not been thoroughly validated. In this study, we aimed to investigate the performance of enhanced computed tomography (CT) or magnetic resonance (MR) imaging by deep learning relative to conventional CT or MR imaging in brain stroke and vascular neurology. We expect that the deep enhanced imaging method can shorten the time stay in the imaging session of stroke patients, optimize the overall imaging quality and improve the patients' care in imaging session.

Interventions

  • Diagnostic test Deep learning imaging enhancement
    Conventional imaging or down-sampling imaging from CT or MR are enhanced by approved deep learning method.

Primary outcome measures

  • The performance of deep enhanced imaging in lesion detection and diagnosis [Time frame: 1 year]

Eligibility criteria

Inclusion criteria

  • suspecting to have experienced stroke or cerebral ischemia and needed to undergo brain imaging and vascular imaging including CT or MRI
  • no history of kidney failure
  • a minimum age of 18 years
  • obtained written informed consent

Exclusion criteria

  • severe movement artifacts
  • incidental finding of tumor lesion or craniocerebral surgery history
  • poor imaging failed to perform deep learning method
  • women who pregnancy

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Case-only

Study locations

China · 1 center
  • Chinese PLA General Hospital — Beijing

Identifiers

NCT: NCT05614193 · AI-301

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗