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Recruiting NCT05600140

Viewing Strategy Training in Children With (Cerebral) Visual Impairment

No phase Interventional Vision Disorders Vision, Low

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Viewing strategy training.
Who it may be relevant to
Registry conditions: Vision Disorders, Vision, Low. Basic parameters: 5 years — 12 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Netherlands
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Viewing Strategy Training in Children With (Cerebral) Visual Impairment: From Spontaneous Eye Movements to a Structured Viewing Strategy

Overview

Viewing strategies are strategies used to process visual Information. Many children with visual impairment seem to lack systematic viewing strategies. However, it is unknown how viewing strategies differ between children with normal vision and children with (cerebral) visual impairment. In addition, viewing strategy training is often adopted in clinical practice, but till date there is no scientific evidence about effectiveness of this approach. The current project has two goals: (1) to measure viewing strategies used by children with normal vision, children with ocular visual impairment and children with CVI, and (2) to evaluate whether training viewing strategies results in more efficiënt visual Information processing.

Interventions

  • Behavioral Viewing strategy training
    Children receive a visual training of viewing strategies (six weeks, 2 times a week, 30 minutes). During the training, children are instructed to use specific viewing strategies (looking in a structured direction which fits the task at hand, zooming in and out / change of visual selective attentional field, visual discrimination). The verbal instructions and exercises are protocol-based. A textbook is used to describe the reactions of the children during training.

Primary outcome measures

  • Changes in reading accuracy after viewing strategy training [Time frame: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4]
  • Changes in reading speed after viewing strategy training [Time frame: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4]
  • Changes in visual search accuracy after training [Time frame: Group A: Day 0, Month 2, Month 8; group B: Day 0, Month 2, Month 4]
  • Changes in visual search speed after training [Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4]
  • Changes in saccade amplitudes during reading and visual search after training [Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4]
  • Changes in fixation duration during reading and search after training [Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4]
  • Changes in average distance between fixation points during conjunction search (EB-VSA) after training [Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4]
Secondary outcome measures (4)
  • Changes in WISC-V visual processing speed index (VSI) after training [Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4]
  • Changes in local visual selective attention after training [Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4]
  • Changes in global visual selective attention after training [Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4]
  • Changes in visual identification speed after training [Time frame: Group A: Day 0, Month 2, Month 8; Group B: Day 0, Month 2, Month 4]

Eligibility criteria

Inclusion criteria typically developing children with normal vision:

  • Age 5-12 years
  • linear distant visual acuity of 0.1 logMAR or better
  • Verbal IQ above 70
  • Absence of developmental disorders or psychiatric problems like ASS or AD(H)D

Inclusion criteria for children with ocular visual impairment:

  • Age 5-12 years
  • Children with linear distance visual acuity better <=1.3logMAR and >0.1 logMAR
  • Intact central visual field (at least > 30 degrees)
  • Children with a verbal IQ above 70
  • Absence of developmental disorders or psychiatric problems like ASS or AD(H)D

Inclusion criteria for children with cerebral visual impairment:

  • Age 5-12 years
  • Linear distance visual acuity <=0.3 logMAR
  • Having the diagnosis CVI (verified by ophthalmologists)
  • Children with a verbal IQ above 70
  • Absence of psychiatric problems like ASS or AD(H)D

Additional inclusion criterion for study 2 (evaluating training effectiveness): children with (cerebral) visual impairment should have an indication for viewing strategy training. Training should not be indicated if children have no problems performing academic tasks (i.e. when speed and accuracy of visual processing is within the normal range). The age range for study 2 is 5-9 years.

Exclusion criteria

  • Children with VI: linear near visual acuity >1.0 logMAR
  • Children with visual field defect < 30 degrees
  • Children with a verbal IQ below 70
  • Children who attended a form of vision training in the past two years
  • Children with psychiatric problems like ASS or AD(H)D
  • Auditory impairment or language impairments
  • Major life events during training

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Allocation
Non-randomized
Model
Parallel assignment
Masking
Open label
Primary purpose
Treatment

Study locations

Netherlands · 1 center
  • Royal Dutch Visio — Nijmegen

Identifiers

NCT: NCT05600140 · NL81584.091.22

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗