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Not yet recruiting NCT05595187

Concomitant Tricuspid Repair in Patients With Left Heart Surgery

No phase Interventional Tricuspid Regurgitation Mitral Regurgitation Cardiopulmonary Bypass

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Tricuspid repair.
Who it may be relevant to
Registry conditions: Tricuspid Regurgitation, Mitral Regurgitation, Cardiopulmonary Bypass. Basic parameters: 18 years — 80 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Concomitant Tricuspid Repair in Patients With Left Heart Surgery: Randomized Controlled Trial

Overview

Tricuspid regurgitation is common in patients with severe left heart diseases, such as degenerative mitral regurgitation. However, the evidence base is insufficient to inform a decision about whether to perform concomitant tricuspid-valve repair during left heart surgery in patients who have mild tricuspid regurgitation. To inform decision making, we will conduct a multicenter, randomized trial to assess the benefits and risks of tricuspid-valve repair at the time of left heart diseases in patients with mild tricuspid regurgitation who were undergoing surgery for left heart surgery.

Interventions

  • Device Tricuspid repair
    Tricuspid repair included suture placement and the type of prosthetic annuloplasty.

Primary outcome measures

  • A composite of adverse cardiovascular events [Time frame: 2 years after surgery at follow-up]

Eligibility criteria

Inclusion criteria

  • Patients undergoing left heart valve surgery with mild tricuspid regurgitation;
  • Patients aged 18-80 years;
  • Agree to participate in this study and sign the informed consent form.

Exclusion criteria

  • Infective endocarditis within 3 months;
  • Primary tricuspid regurgitation;
  • Isolated tricuspid regurgitation
  • Lactating women and suspected pregnant or pregnant women;
  • Patients with mental disorders, drug and alcohol dependence;
  • Those who participated in other clinical trials one month before the trial;
  • Refusal to participate in this study without informed consent.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Double blind
Primary purpose
Treatment

Study locations

China · 1 center
  • The First Affiliated Hospital of Nanjing Medical University — Nanjing

Identifiers

NCT: NCT05595187 · JPH-2022

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗