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Recruiting NCT05566392

Longterm Influence of Pediatric Long COVID Syndrome

— Observational COVID-19-Associated Encephalitis Long COVID

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Brain MRI.
Who it may be relevant to
Registry conditions: COVID-19-Associated Encephalitis, Long COVID. Basic parameters: 6 years — 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Taiwan
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Longterm Influence of Pediatric Long COVID Syndrome on the Neuropsychiatric Function, Social Function, Neuroimage, and Gut Microbiota

Overview

We enroll pediatric patients who were diagnosed COVID-19 for main observation target. We will perform brain MRI and neuropsychiatric evaluation 4-6 months after COVID-19 diagnosed. We also enroll healthy age- and gender-matched participant for cross-over comparison. We will perform same evaluation process one year later for longitudinal evaluation

Interventions

  • Diagnostic test Brain MRI
    Brain MRI including diffusion spectrum image, and functional MRI Interview with questionnaires for neuropsychiatric evaluation Near infrared spectroscopy and resting-state connectivity evaluation

Primary outcome measures

  • Difference between COVID and healthy group [Time frame: 1 years after enrollment for primary evaluation]

Eligibility criteria

Inclusion criteria

  • Age 6-18 years old
  • Has been diagnosed COVID-19 before

Exclusion criteria

  • History of neuropsychiatric disorders
  • Have some device not allowed for MRI

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Case-crossover

Study locations

Taiwan · 1 center
  • National Taiwan University Children Hospital Pediatric Neurology Department — Taipei

Identifiers

NCT: NCT05566392 · 202208086RIND

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗