The Validation and Development of Termination-of-Resuscitation (TOR) Rules in OHCA Patients in Asia Countries
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: termination of resuscitation rules.
- Who it may be relevant to
- Registry conditions: Out-Of-Hospital Cardiac Arrest. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Taiwan
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
The Validation and Development of Termination-of-Resuscitation (TOR) Rules in Patients Following Out-of-Hospital Cardiac Arrest (OHCA) in Asia Countries
Overview
Objectives/Hypotheses 1. Prehospital termination-of-resuscitation (TOR) rules were developed in North American and European sites. Whether they remained valid in different geographic, ethnic, and cultural background areas is still under debate. 2. Differences in characteristics of out-of-hospital cardiac arrests (OHCAs) and configurations of emergency medical service (EMS) between the Western and Asian countries, including relatively lower rate of presenting shockable rhythm (i.e. ventricular fibrillation / ventricular tachycardia; VF/VT), lower rates of bystander CPR, less advanced life support (ALS) implementation, and less public access defibrillators, might create potential threats to the prediction accuracy of TOR rules. 3. We aim to conduct a study to validate the performance of ever published TOR rules in Asian OHCA population, including non-traumatic, traumatic, and pediatric OHCA patients. Furthermore, assess the possible variables that may impact the performance of TOR rules. 4. We also aim to develop new TOR rules based on PAROS registry for Asia population, focusing on non-traumatic, traumatic, and pediatric OHCA patients, respectively.
Interventions
- Other termination of resuscitation rules
Use retrospective data to analyze the accuracy termination of resuscitation rules and further develope a termination of resuscitation rule.
Primary outcome measures
- survival to hospital discharge [Time frame: survival to 30-day hospitalisation]
Secondary outcome measures (1)
- Cerebral Performance Categories Scale (CPC) [Time frame: CPC within 30-day hospitalisation]
Eligibility criteria
Inclusion criteria
- out of hospital cardiac arrest (OHCA) patients
Exclusion criteria
- age <18 years
- non-EMS transport to the emergency department
- obvious signs of death (e.g. decapitation, rigor mortis, lividity, and decapitation) or having do-not-resuscitate (DNR) orders
- missing data despite meeting the inclusion criteria.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Other
Study locations
Taiwan · 1 center
- National Taiwan University — Taipei
Identifiers
NCT: NCT05545176 · 202206030RINC