Recruiting NCT05514769
Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty.
- Who it may be relevant to
- Registry conditions: Proximal Gastric Adenocarcinoma, Gastric Cancer, Gastroesophageal Reflux Disease. Basic parameters: 18 years — 85 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
This research is designed to compare proximal gastrectomy anterior anastomosis with pyloroplasty with esophagogastric anastomosis for gastric cancer. Gastroesophageal reflux disease, postoperative quality of life, short term outcomes, and long term outcomes will be compared.
Interventions
- Procedure Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty
The location of the anastomosis in the anterior of the gastric stump. Pyloroplasty is added in the procedure
Primary outcome measures
- Gastroesophagus reflux disease apprised by ph monitoring [Time frame: 6 months]
- Gastroesophagus reflux disease apprised by questionnaire [Time frame: 6 months]
Secondary outcome measures (2)
- Surgical complications of proximal gastrectomy for gastric cancer [Time frame: 1 year]
- Long-term outcome [Time frame: 5 years]
Eligibility criteria
Inclusion criteria
- Histologically confirmed adenocarcinoma of the stomach, T1-T4 stages.
- Eastern Cooperative Oncology Group performance status of 0 or 1.
- Adequate organ function.
Exclusion criteria
- Patients had distant metastasis.
- oesophageal invasion of more than 3 cm.
- Borrmann type 4 or large (more than 8 cm) type 3 carcinoma.
- Previous chemotherapy or radiation therapy for any other malignancies.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Single blind
- Primary purpose
- Treatment
Study locations
China · 1 center
- Yunhong Tian — Nanchong
Identifiers
NCT: NCT05514769 · 20220720