Recruiting NCT05462366
Omics Sequencing of Specimen Derived From Mother-Infant-Pairs
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Sample collection.
- Who it may be relevant to
- Registry conditions: Healthy, Breast-milk Collection, Feces. Basic parameters: up to 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
The investigators aim to collect breast-milk and feces from the participants, and apply culture techniques as well as omics sequencing technology to probe into the microbial and metabolomic signature of the specimens.
Interventions
- Other Sample collection
Collect breast-milk and feces from mother-infant-pairs.
Primary outcome measures
- Compare the omics differences of the specimens between the experimental and control groups [Time frame: 2021.7.1-2026.12.30]
- Compare the microbial feature differences of the specimens between the experimental and control groups [Time frame: 2021.7.1-2026.12.30]
Secondary outcome measures (1)
- Compare the health status differences between the experimental and control groups [Time frame: 2021.7.1-2026.12.30]
Eligibility criteria
Inclusion criteria
- healthy pregnant women aged between 20y and 40y.
- Vaginal birth
- BMI<23.5 before pregnancy
- Infants' birth weight, between 2500g and 4000g.
Exclusion criteria
- gestational diabetes
- diagnosis of depressive disorder during pregnancy
- gestational hypertension
- diagnosis of other diseases during pregnancy
- Under probiotics or antibiotic treatment from 3 months prior to pregnancy till 3 months after delivery
- histrory of smoking and drinking alcohol
- history of diarrhea from 3 months prior to pregnancy till 3 months after delivery
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Family-based
Study locations
China · 1 center
- Zhujiang Hospital — Guangzhou
Identifiers
NCT: NCT05462366 · ZhujiangHFCYXZX