Menu
Recruiting NCT05440929

Evaluation of the Acceptability, Appropriateness, and Feasibility/Usability of a Metastatic Breast-cancer Specific Prognostic Calculator Among Clinicians

Observational Metastatic Breast Cancer End of Life

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Clinician Qualitative Interview.
Who it may be relevant to
Registry conditions: Metastatic Breast Cancer, End of Life. Basic parameters: No limits · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Overview

I this qualitative study, Investigators will conduct semi-structured interviews with clinicians that are involved in the care of patients with breast cancer to evaluate the acceptability, appropriateness, and feasibility/usability of a metastatic breast cancer-specific prognostic tool. These interviews will be conducted by the UNC CHAI Core and will continue until thematic saturation (estimated 10 participants). The investigators will code the qualitative data using emerging themes, guided by a well-established implementation science theory, the Consolidated Framework for Implementation Research (CFIR). The information gained from these studies will inform an implementation approach to increase the usability and acceptability of a novel prognostic tool to assist oncologists in the prognosis of patients with metastatic breast cancer.

Detailed description

If this study is successful, Investigators will implement an MBC-specific prognostic tool to help clinicians identify patients who are at high risk of death in the next 30 days. Based on the input from clinicians in this proposal, as well as additional qualitative studies with patients and families, Investigators will design an implementation protocol to inform how to use this tool in clinical practice. Rather than simply publishing a prognostic tool that may not be adopted into practice, this project aims to ensure successful implementation of an evidence-based tool into the routine care of patients with MBC. Doing so will serve as an important step towards identifying high-risk patients and connecting ort to ensure high-quality, patient-centered end-of-life care.

Interventions

  • Behavioral Clinician Qualitative Interview
    Interviews will be conducted by experienced qualitative researchers from the UNC Connected Health for Applications \& Interventions (CHAI) Core. The interview will be conducted over the phone or secure videoconferencing. The interview will be conducted in a semi-structured fashion using an interview guide. However, because the purpose of this semi-structured qualitative interview study is to determine which themes participants identify as important, the exact content of each interview will diffe

Primary outcome measures

  • Key barriers for use a metastatic breast cancer-specific prognostic tool [Time frame: 12 months]
  • Key facilitators for use of a metastatic breast cancer-specific prognostic tool [Time frame: 12 months]
Secondary outcome measures (2)
  • Key barriers for discussion of prognosis between oncology clinicians and patients with metastatic breast cancer [Time frame: 12 months]
  • Key facilitators for discussion of prognosis between oncology clinicians and patients with metastatic breast cancer [Time frame: 12 months]

Eligibility criteria

Inclusion criteria

  • Verbal informed consent obtained to participate in the study.
  • Subject is willing and able to comply with study procedures based on the judgement of the investigator or protocol designee.
  • Physician, nurse practitioner, physician assistant, or nurse navigator
  • At least 6 months of experience in the clinical care of patients with metastatic breast cancer in the United States.

Exclusion criteria

  • Non-English Speaking

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: Yes

Study design

Observational model
Ecologic or community

Study locations

United States · 1 center
  • University of North Carolina — Chapel Hill

Identifiers

NCT: NCT05440929 · LCCC2207

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗