Menu
Recruiting NCT05439863

TAVR for Aortic Valve Disease

Observational Aortic Valve Disease

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: transcatheter heart valve.
Who it may be relevant to
Registry conditions: Aortic Valve Disease. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Transcatheter Aortic Valve Replacement for Severe Aortic Valve Disease: Multi-center, Real-word Registry

Overview

Transcatheter aortic valve replacement (TAVR) has became an important treatment of severe aortic stenosis (AS). Several randomized clinical trials showed that TAVR was non-inferior or superior to surgical aortic valve replacement (SAVR). However, many different issues have emerged: TAVR in younger patients? valve leaflet thrombosis? transcatheter valve durability? coronary reaccess after TAVR? TAVR in bicuspid aortic valve? TAVR in aortic regurgitation? etc. Hence, a prospective, multicenter database is created to provide the real-word data for these questions.

Interventions

  • Device transcatheter heart valve
    patients with severe aortic valve disease underwent transcatheter heart valve

Primary outcome measures

  • all-cause death during follow-up [Time frame: 5 years]
Secondary outcome measures (1)
  • cardiac death during follow-up [Time frame: 5 years]

Eligibility criteria

Inclusion criteria

  • Clinical diagnosis of severe aortic stenosis or aortic regurgitation
  • Patients undergo transcatheter aortic valve replacement

Exclusion criteria

patients refuse the clinical follow-up

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 1 center
  • Nanjing First Hospital — Nanjing

Identifiers

NCT: NCT05439863 · NanjingValve Registry

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗