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Recruiting NCT05433467

CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection

No phase Interventional Cirrhosis, Liver Hepatocellular Carcinoma

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: CT-guided localization for micro hepatocellular carcinoma before surgical resection.
Who it may be relevant to
Registry conditions: Cirrhosis, Liver, Hepatocellular Carcinoma. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

The Feasibility of CT-guided Localization for Micro Hepatocellular Carcinoma Before Surgical Resection

Overview

In this project, the preoperative anatomical location of micro hepatocellular carcinoma under the guidance of CT can provide guidance for accurate surgical resection. It may also shorten the operation time and reduce intraoperative bleeding.

Detailed description

General and basic information of the patients included in the study was collected. After preoperative preparation was completed, on the day of surgery, disposable pulmonary nodular localization needle (Ningbo Sonjiecang Biological Technology Co., LTD., Model: SS510-10) was used for the localization of micro hepatocellular carcinoma that could be found by preoperative CT enhancement or MRI. After the micro hepatocellular carcinoma was located under the guidance of CT, and then the patient was sent to the operating room. During the operation, the lesion was removed according to the tail line of the positioning needle and the position of the positioning needle.

Interventions

  • Procedure CT-guided localization for micro hepatocellular carcinoma before surgical resection
    After preoperative preparation was completed, on the day of surgery, disposable pulmonary nodular localization needle (Ningbo Sonjiecang Biological Technology Co., LTD., Model: SS510-10) was used for the localization of micro hepatocellular carcinoma that could be found by preoperative CT enhancement or MRI. After the micro hepatocellular carcinoma was located under the guidance of CT, and then the patient was sent to the operating room. During the operation, the lesion was removed according to

Primary outcome measures

  • The position of the needle [Time frame: During operation]
Secondary outcome measures (2)
  • Operation time [Time frame: During operation]
  • Intraoperative bleeding [Time frame: During operation]

Eligibility criteria

Inclusion criteria

  • Be at least 18 years old and give informed consent to participate in the study
  • A preoperative (clinical, radiological, or histological) diagnosis of cirrhosis of the liver due to any cause.
  • micro hepatocellular carcinoma (diameter less than 1cm).
  • Preoperative CT plain scan could not find the lesion, and preoperative B-ultrasound could not find the lesion.
  • Preoperative CT enhancement or MRI can detect the lesion.

Exclusion criteria

  • Child-Pugh grade C
  • Uncontrolled Hypertension
  • Severe lung dysfunction
  • Severe cardiac dysfunction

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Treatment

Study locations

China · 1 center
  • Clinical Medical College, Yangzhou University — Yangzhou

Identifiers

NCT: NCT05433467 · YZUC-012

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗