Menu
Recruiting NCT05426408

Stockholm Myocardial Infarction with Nonobstructive Coronaries Study 3

No phase Interventional Myocardial Infarction with Nonobstructive Coronary Arteries

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Cardiac magnetic resonance imaging to study coronary microvascular dysfunction.
Who it may be relevant to
Registry conditions: Myocardial Infarction with Nonobstructive Coronary Arteries. Basic parameters: 35 years — 79 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Sweden
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Stockholm Myocardial Infarction with Nonobstructive Coronaries Study 3 - Pilot Study of Prevalence of Coronary Microvascular Dysfunction in Myocardial Infarction with Nonobstructive Coronary Arteries

Overview

The present pilot study will investigate the prevalence of CMD in an unselected cohort of patients with the working diagnosis MINOCA and to study if the diagnostic yield can be improved by adding adenosine to the CMR investigation. Patient will be their own controls.

Interventions

  • Diagnostic test Cardiac magnetic resonance imaging to study coronary microvascular dysfunction
    Myocardial perfusion mapping will be investigated after administration of adenosine

Primary outcome measures

  • Diagnostic yield [Time frame: Through investigation completion, usually 2 hours]
Secondary outcome measures (3)
  • Prevalence of CMD in MINOCA [Time frame: Through investigation completion, usually 2 hours]
  • Prevalence of CMD in different final MINOCA diagnoses [Time frame: Through investigation completion, usually 2 hours]
  • Angina pectoris [Time frame: 3 Months]

Eligibility criteria

Inclusion criteria

  • a suspected diagnosis of MINOCA or takotsubo syndrome with coronary angiography without diameter stenosis ≥50%
  • age 35-80 years
  • reading and writing proficiency in Swedish

Exclusion criteria

  • Claustrofobia
  • Arrythmia and/or pacemaker (atrial fibrillation and AV-block I- III)
  • Asthma or severe chronic obstructive lung disease
  • eGFR < 30 ml/min
  • spontaneous coronary artery dissection
  • acute pulmonary embolism
  • acute myocardial infarction type 2
  • cardiomyopathy other than takotsubo syndrome
  • a previous myocardial infarction due to CAD

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Diagnostic

Study locations

Sweden · 1 center
  • Per Tornvall — Stockholm

Identifiers

NCT: NCT05426408 · SMINC-3

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗