Study of Disrupted Sleep in Somali Americans
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: 24 hour blood pressure (BP) monitoring, Polysomnography.
- Who it may be relevant to
- Registry conditions: Hypertension, Sleep Disorder, Healthy. Basic parameters: 18 years — 70 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Disrupted Sleep in Somali Americans - Implications for Hypertension Risk
Overview
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.
Interventions
- Diagnostic test 24 hour blood pressure (BP) monitoring
24-hour ambulatory BP measuring device and blood pressures will be measured every 20 minutes to half hour - Diagnostic test Polysomnography
Measurements will include electroencephalogram, electromyogram, electrooculogram, electrocardiogram, breathing patterns of chest and abdomen, nasal and oral airflow and oxygen saturation. Sleep stages and apneas will be scored in accordance with validated American Academy of Sleep Medicine standards.
Primary outcome measures
- Undiagnosed sleep deficiency-short sleep [Time frame: 1 night sleep study, approximately 8-9 hours]
- Undiagnosed sleep deficiency-insomnia [Time frame: 1 night sleep study, approximately 8-9 hours]
- Undiagnosed sleep deficiency-obstructive sleep apnea (OSA) [Time frame: 1 night sleep study, approximately 8-9 hours]
- Disrupted sleep [Time frame: 1 night sleep study, approximately 8-9 hours]
- Blood pressure (BP) during wakefulness [Time frame: Day 2]
- Blood pressure (BP) during sleep [Time frame: Day 2]
Eligibility criteria
Inclusion criteria
- Subjects diagnosed with no known history of hypertension, diabetes, or sleep disorders.
- Self-identify as Somali.
- Adult males and females who are older than 18 years of age.
Exclusion criteria
- Anyone under 18 years or over 70 years.
- Positive pregnancy.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Ecologic or community
Study locations
United States · 1 center
- Mayo Clinic in Rochester — Rochester
Publications
- Greenlund IM, Bock JM, Govindan N, Kantas D, Singh P, Covassin N, Somers VK. Blood Pressure and Heart Rate Response to Orthostasis in Somali Americans. J Racial Ethn Health Disparities. 2026 Jun;13(3):1961-1966. doi: 10.1007/s40615-025-02389-7. Epub 2025 Mar 15. PMID 40088388
- Greenlund I, Bock J, Govindan N, Kantas D, Singh P, Covassin N, Somers V. Blood Pressure and Heart Rate Response to Orthostasis in Somali Americans. Res Sq [Preprint]. 2024 Oct 21:rs.3.rs-4925722. doi: 10.21203/rs.3.rs-4925722/v1. PMID 39502777
Identifiers
NCT: NCT05411029 · 22-004192