Identification of Risk Factors for Cardiovascular Disease and Cancer in Korean Population: A Prospective Cohort Study
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cardiovascular Diseases, Malignancy, Risk Factor. Basic parameters: from 19 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- South Korea
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Cancer and cardiovascular disease are the global leading causes of death. These two disease entities are multifactorial disease that are caused by several factors. The aim of this prospective cohort study was to investigate the status of risk factors profiles and health related behavior in Korean population, and to discover novel risk factors associated with the occurrence of endpoint events.
Detailed description
This is a single center, observational, prospective cohort study. The primary outcomes include the incidence of MACE (major adverse cardiovascular events) and the incidence of any malignancy. We plan to collect the baseline information at enrollment and the occurrence of clinical endpoint events will be followed for at least 10 years. The study will enroll 510,000 subjects aged ≥19 years who underwent a general health screening in Korea.
Primary outcome measures
- Major adverse cardiovascular event (MACE) [Time frame: 10 year]
- Incidence of malignancy [Time frame: 10 year]
Secondary outcome measures (5)
- All-cause death [Time frame: 10 year]
- Cardiovascular death [Time frame: 10 year]
- Myocardial infarction [Time frame: 10 year]
- Stroke [Time frame: 10 year]
- Cancer related mortality [Time frame: 10 year]
Eligibility criteria
Inclusion criteria
- Men or women aged 19 years and older who underwent a general health screening at the health promotion center of Ulsan University Hospital (Ulsan, Korea)
- Subjects have to agree to participate by signing a consent
Exclusion criteria
- Subjects who cannot or reject to sign the consent form.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
South Korea · 1 center
- Ulsan University Hospital — Ulsan
Identifiers
NCT: NCT05389956 · 2021-12-014-003