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Recruiting NCT05377216

Characterization of Cardiac Electrophysiological Effects of Autonomic Neuromodulation

Early Phase I Interventional Ventricular Tachycardia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Stellate Ganglion Block.
Who it may be relevant to
Registry conditions: Ventricular Tachycardia. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

Prospective cohort study evaluating the electrophysiologic and biochemical effects of stellate ganglion block in patients with ventricular tachycardia.

Interventions

  • Drug Stellate Ganglion Block
    Left sided percutaneous stellate ganglion block

Primary outcome measures

  • Ventricular Effective Refractory Period [Time frame: 30 minutes following stellate ganglion block]
Secondary outcome measures (2)
  • Ventricular Arrhythmia Inducibility [Time frame: 30 minutes following stellate ganglion block]
  • Neuropeptide Y [Time frame: 30 minutes following stellate ganglion block]

Eligibility criteria

Inclusion criteria

  • Planned catheter based VT ablation
  • Age at least 18 years

Exclusion criteria

  • Pregnancy
  • Contraindication to SGB or VT ablation
  • Hypersensitivity of local anesthetic of amide type
  • Hemodynamic instability during the procedure prior to the study protocol

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Basic science

Study locations

United States · 1 center
  • Hospital of the University of Pennsylvania — Philadelphia

Identifiers

NCT: NCT05377216 · 851066

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗