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Recruiting NCT05373810

Registration Study Sarcoma

Observational Sarcoma

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Surgery.
Who it may be relevant to
Registry conditions: Sarcoma. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Netherlands
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Registration Study on Bone and Soft Tissue Sarcoma - An Observational Cohort Study -

Overview

The prospective and retrospective data collection on bone and soft tissue sarcoma is an observational cohort study aimed to collect clinical data and patient reported outcomes of all patients who have been diagnosed with bone or soft tissue sarcoma in the Netherlands. All patients diagnosed with bone or soft tissue sarcoma who are treated, planned for treatment or currently being treated, will be asked to participate in this project.

Detailed description

The main objectives of this project are:

* To improve the knowledge and therefore the treatment care, in patients with bone or soft tissue sarcoma in the Netherlands * To start an observational cohort study of bone and soft tissue sarcoma patients from their primary diagnosis until death * To prospectively and retrospectively collect data on medical history, co-morbidities, baseline clinical parameters, imaging results, pathology results, tumor characteristics, treatment, treatment outcomes, functional outcome, cosmetic outcome, hospital stays and interventions. * To collect data on health related quality of life and work ability, to collect data on patient reported outcomes measures. * To create a continuous basis for a large variety of research purposes including:

* Prognostic and predictive research * Health care policies and cost-effectiveness studies

Interventions

  • Other Surgery
    all interventions are allowed

Primary outcome measures

  • Progression free survival [Time frame: up to 10 years]
Secondary outcome measures (4)
  • Health related quality of life [Time frame: up to 5 years]
  • grade 3/4 serious adverse events [Time frame: up to 5 years]
  • Disease free survival [Time frame: up to 10 years]
  • Overall survival [Time frame: up to 10 years]

Eligibility criteria

Inclusion criteria

  • Histologically proven bone or soft tissue sarcoma, excluding Gastrointestinal Stromal Tumours

Exclusion criteria

  • Altered mental status that would prohibit the understanding of and giving of informed consent

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Netherlands · 2 centers
  • Radiotherapiegroep — Arnhem
  • Radboudumc — Nijmegen

Identifiers

NCT: NCT05373810 · NL69559.091.19

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗