National Registry and Cohort Study of Pulmonary Vascular Disease
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: The clinical course and disease management.
- Who it may be relevant to
- Registry conditions: Pulmonary Arterial Hypertension. Basic parameters: No limits · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
This is a observational、multicenter, prospective cohort study for patients with pulmonary hypertension (PH). The purposes of this study were to evaluate the etiology、clinical characteristics、treatment modalities, and outcomes of patients with PH；also to set up registration system of PH in China, to build a database of Chinese PH, to establish a web-based international standard data acquisition system for PH and a multicenter clinical research platform. The results of the study will provide a basis for the future national health policy for prevention and treatment of PH.
Interventions
- Combination product The clinical course and disease management
The clinical course and disease management of pulmonary hypertension patients
Primary outcome measures
- All-cause Death [Time frame: 5 years]
Secondary outcome measures (1)
- Number of Participants with Clinical Worsening [Time frame: 5 years]
Eligibility criteria
Inclusion criteria
- Newly diagnosed or previously diagnosed patients with PH.
- Documentation of mean pulmonary arterial pressure (mPAP) >20 mm Hg by right heart catheterization, performed at any time prior to study enrollment.
Exclusion criteria
- Have not had documentation of hemodynamic criteria for PH by right heart catheterization at some time preceding study entry and following development of symptoms associated with PH.
- Do not meet the required hemodynamic criteria for entry into the study.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
China · 13 centers
- Guangdong Provincial Peoples Hospital — Guangzhou
- Nanjing First Hospital — Nanjing
- General Hospital of Tianjin Medical University — Tianjin
- Beijing Anzhen Hospital of Capital Medical University — Beijing
- China-japan Friendship Hospital — Beijing
- Xiangya Second Hospital, Central South University — Changsha
- West China Hospital, Sichuan University — Chendu
- Nanjing Drum Tower Hospital — Nanjing
- … and 5 more centers
Identifiers
NCT: NCT05368467 · NMU20220505