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Recruiting NCT05342233

Comparison of Conservative and Endovascular Treatment for Spontaneously Isolated Superior Mesenteric Artery Dissection

— Observational Spontaneous Isolated Superior Mesenteric Artery Dissection

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
This is an observational study: the protocol does not assign a study treatment.
Who it may be relevant to
Registry conditions: Spontaneous Isolated Superior Mesenteric Artery Dissection. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Comparison of Conservative and Endovascular Treatment for Spontaneously Isolated Superior Mesenteric Artery Dissection: A Real-world, Multicenter, Observational Study

Overview

Spontaneous isolated superior mesenteric artery dissection(SISMAD) is an increasingly diagnosed disease. However, prospective, multicenter studies that can provide evidence to support clinical decisions are very limited. This study aims to compare the therapeutic efficacy of conservative and endovascular treatment for SISMAD.

Primary outcome measures

  • Mortality [Time frame: up to 5 years]
  • Rate of symptom relief [Time frame: up to 5 years]
Secondary outcome measures (4)
  • Reintervention rate [Time frame: Follow-up period（ 5 years）]
  • Recurrence rate [Time frame: Follow-up period（5 years）]
  • Disease-related complications [Time frame: Follow-up period（5 years）]
  • Complete remodeling rate of superior mesenteric artery dissection [Time frame: Follow-up period（5 years）]

Eligibility criteria

Inclusion criteria

  • Aged 18 and above;
  • Isolated superior mesenteric artery dissection with clear symptoms or history and confirmed by CTA
  • Signed informed consent forms, willing to receive treatments

Exclusion criteria

  • Symptoms are severe and patients need exploratory laparotomy;
  • Patients with aortic dissection, iliac artery dissection, or autoimmune vasculitis;
  • Patients with mental illness cannot cooperate subjectively;
  • Patients who are allergic to contrast agents, or contraindicated to conservative treatment drugs, and cannot be treated with drugs;
  • Pregnancy and breastfeeding women, or patients who have recent birth plans;
  • Patients who are participating in other clinical projects;
  • Patients are not suitable to participate in this study.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 1 center
  • Xiangya Hospital of Central South University — Changsha

Identifiers

NCT: NCT05342233 · ISMAD2022

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗