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Recruiting NCT05325580

Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department

Phase III Interventional Head Pain

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Magnesium sulfate.
Who it may be relevant to
Registry conditions: Head Pain. Basic parameters: 18 years — 85 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Tunisia
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Intravenous Magnesium Sulfate Vs Placebo to Treat Non-traumatic Acute Headaches in the Emergency Department

Overview

Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department

Detailed description

Rate of Intravenous Magnesium Sulfate Vs Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department

Interventions

  • Drug Magnesium sulfate
    magnesium group 1g paracetamol + 20 min infusion of 2 g magnesium in 150 ml of saline serum and Placebo Group 1g paracetamol + 20 min infusion of 150 ml of saline serum

Primary outcome measures

  • Intravenous Magnesium Sulfate to Treat Non -Traumatic Acute Headaches in the Emergency Department [Time frame: 1day]
Secondary outcome measures (1)
  • Placebo to Treat Non -Traumatic Acute Headaches in the Emergency Department [Time frame: 1 day]

Eligibility criteria

Inclusion criteria

  • informed consent
  • age >18 years
  • Acute non-traumatic acute headaches
  • patients treated in ED
  • Magnesium sulfate and aspirin administered intravenously (IV)

Exclusion criteria

  • Current regular use of analgesics, anticonvulsants or antidepressants
  • Renal disorder with a low glomerular filtration rate (<60 ml/min)
  • Neuromuscular disorder
  • Pregnant woman
  • Contrindication
  • Allergy to NSAID
  • Traumatic Headache
  • Chronic headache ( headache occurring at least 15 days per month for at least 3 months)
  • Hemodynamic instability

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Triple blind
Primary purpose
Treatment

Study locations

Tunisia · 1 center
  • University of Monasrtir — Monastir

Identifiers

NCT: NCT05325580 · Emergency Monastir

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗