Evaluating a Community-Based Behaviour Change Communication Model to Prevent Cholangiocarcinoma in Khon Kaen, Thailand
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: eCHEC program.
- Who it may be relevant to
- Registry conditions: Cholangiocarcinoma, Liver Fluke-Related Cholangiocarcinoma, Opisthorchiasis. Basic parameters: from 20 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Thailand
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Liver cancer, specifically cholangiocarcinoma (CCA), is very common in different areas in Thailand. Many factors make this cancer more common, such as liver fluke infection, older age, eating raw fish, family history of cancer, alcohol intake, taking certain medicines (praziquantel), low intake of fresh vegetable, and low education. In 2015, researchers from Khon Kaen University developed the Community-based Health Education and Communication (CHEC) program to prevent liver cancer caused by liver flukes in communities of the Khon Kaen province, Thailand. The main aim of this 5-year research study is to enhance the CHEC program to prevent liver cancer, and test if it is effective in improving the knowledge and behaviours of community residents regarding how to prevent liver cancer. This study will take place in Khon Kaen, Thailand. Other aims are to: 1. Increase understanding in the community that make it difficult to prevent liver cancer, as well as community characteristics that can help prevent liver cancer; 2. Incorporate the program we develop in healthcare to prevent liver cancer in Thailand.
Interventions
- Behavioral eCHEC program
The eCHEC program is the enhanced Community-based Health Education and Communication (CHEC) model to prevent O. viverrini in an effort to decrease cholangiocarcinoma (CCA) in Khon Kaen, Thailand
Primary outcome measures
- Intake of raw fish [Time frame: 12 months]
- Intake of fruits and vegetables [Time frame: 12 months]
- Smoking [Time frame: 12 months]
- Alcoholic beverage intake [Time frame: 12 months]
- Praziquantel use [Time frame: 12 months]
- Stool test (proportion of stool test concentration) [Time frame: 12 months]
- Stool test (mean concentration) [Time frame: 12 months]
- Stages of change for risk behaviours affecting the development of CCA. [Time frame: 12 months]
Secondary outcome measures (6)
- Knowledge of preventative measures against CCA [Time frame: 12 months]
- BMI [Time frame: 12 months]
- Waist circumference [Time frame: 12 months]
- Blood pressure [Time frame: 12 months]
- Health literacy [Time frame: 12 months]
- Quality of life [Time frame: 12 months]
Eligibility criteria
Inclusion criteria
- any individual residing in one of the 16 villages selected in the Khon Kaen province of Thailand, aged 20 and older
Exclusion criteria
- any individual 19 years or younger
- any individual not residing in one of the 16 pre-selected villages in the Khon Kaen province of Thailand
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Prevention
Study locations
Thailand · 1 center
- Khon Kaen University — Phu Wiang
Identifiers
NCT: NCT05321992 · 0609004105 · 13955