Network Connectivity and Temporal Processing in Adolescents Who Stutter
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Rhythm discrimination.
- Who it may be relevant to
- Registry conditions: Stuttering, Childhood, Stuttering. Basic parameters: 9 years — 13 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Subcortical Network Connectivity and Temporal Processing in Children With Persistent and Recovered Stuttering
Overview
The specific purpose of this clinical trial is to compare performance on rhythm perception and production tasks between children who stutter and children who do not stutter. The overall project also aims to investigate how performance on rhythm tasks may be related to brain activity (non-clinical trial).
Detailed description
Participants in the clinical trial portion of this study will complete rhythm discrimination and finger tapping experiments once a year for 3 years. The study team will compare performance between groups. Participants will also participate in the non-trial portion of the project that includes having magnetic resonance imaging (MRI) each year for 3 years.
Interventions
- Behavioral Rhythm discrimination
Participants will complete a rhythm discrimination task once per year for 3 years.
Primary outcome measures
- Rhythm discrimination (d') [Time frame: Year 1]
- Rhythm discrimination (d') [Time frame: Year 2]
- Rhythm discrimination (d') [Time frame: Year 3]
Eligibility criteria
Inclusion Criteria Children who stutter:
- English as primary language
- Current or past stuttering diagnosis
Inclusion Criteria Children who do not stutter:
- English as primary language
Exclusion Criteria Children who stutter:
- Diagnosed/under treatment for any neurological or psychiatric conditions
- Head trauma with loss of consciousness
- Major medical illness
- Hearing loss- Language/motor delay (below -2 standard deviations on standardized assessments)
- Face, motor, or reflex abnormalities
Exclusion Criteria Children who do not stutter:
- Personal or family history of stuttering
- Diagnosed/under treatment for any neurological or psychiatric conditions
- Head trauma with loss of consciousness
- Major medical illness
- Hearing loss
- Language/motor delay (below -2 standard deviations on standardized assessments
- Face, motor, or reflex abnormalities
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Non-randomized
- Model
- Parallel assignment
- Masking
- Open label
- Primary purpose
- Basic science
Study locations
United States · 1 center
- University of Michigan — Ann Arbor
Identifiers
NCT: NCT05286151 · HUM00196133 · 2R01DC011277