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Recruiting NCT05277129

The Immune Response to Stroke

— Observational Stroke, Acute Dementia

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Analysis of post-stroke immune responses.
Who it may be relevant to
Registry conditions: Stroke, Acute, Dementia. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Norway
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

Some patients develop cognitive decline after a stroke, but we don't always understand the mechanisms. It has been proposed that a proportion of the patients develop an autoimmune immune response, and that this could potentially explain the cognitive decline in some of the patients. The current study aims to investigate this hypothesis in a subgroup of patients with stroke.

Interventions

  • Other Analysis of post-stroke immune responses
    Analysis of immune responses in peripheral blood

Primary outcome measures

  • The B cell and T cell response in peripheral blood [Time frame: 1 day (subject inclusion)]

Eligibility criteria

Inclusion criteria

  • Stroke < 72 h
  • Age > 18 years

Exclusion criteria

  • Brain hemorrhage verified by CT or MRI scan
  • Previous or present immunological disease or other serious comorbidity
  • Ongoing immune respons after infection or vaccination < 1 month
  • Cognitive without ability to understand and/or give an informed consent to participate in the study

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Norway · 1 center
  • Akershus University Hospital — Lørenskog

Identifiers

NCT: NCT05277129 · 2019/1252

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗