Trigeminal Neuralgia Electrophysiology
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Trigeminal Electrophysiology.
- Who it may be relevant to
- Registry conditions: Trigeminal Neuralgia. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Trigeminal Evoked Responses to Improve Rhizotomy
Overview
The study intervention is to perform standard somatosensory evoked responses limited to the face during rhizotomy procedures of the gasserian ganglion (trigeminal ganglion) for the treatment of trigeminal neuralgia. The evoked responses will be measured at two locations before and after the clinical rhizotomy including: the standard contralateral scalp (EEG) and at the gasserian ganglion through an FDA-approved recording electrode.
Interventions
- Procedure Trigeminal Electrophysiology
This study will pilot and test the feasibility of introducing electrophysiology into the routine rhizotomy procedure by including trigeminal somatosensory evoked potentials (TSEPs) and recording from electrodes at the level of the ganglion.
Primary outcome measures
- Determine the feasibility of measuring trigeminal somatosensory evoked potentials to improve personalized mapping during percutaneous rhizotomy [Time frame: 3 years]
Eligibility criteria
Inclusion Criteria (TGN):
- Adults of 18 years or older
- Scheduled to undergo percutaneous rhizotomy for facial pain
Exclusion Criteria (TGN):
- Facial pain of unclear origin (i.e. not clearly TGN pain)
- Rhizotomy procedure canceled
Inclusion Criteria (Healthy controls)
- Adults of 18 years or older
Exclusion Criteria (Healthy Controls)
- Diagnosis or history of facial pain such as TMD or TGN
- History of migraine
- History of any functional pain disorder: fibromyalgia, IBS, CRPS
- Recent chronic pain (within last month)
- Unwilling to participate for two hours in lab
- Current acute pain
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- University of Minnesota — Minneapolis
Identifiers
NCT: NCT05269472 · NSU-2022-30582