Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Liver transplantation.
- Who it may be relevant to
- Registry conditions: Colorectal Cancer Metastatic. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Liver Transplantation From Living Donors For Treatment Of Non-Resectable Colorectal Carcinoma Liver Metastases: A Registry Study
Overview
The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.
Detailed description
The goal of this study is to create a data registry to capture clinical, pathologic, and molecular data/outcomes for patients with metastatic colorectal cancer who undergo live donor liver transplantation.
Our primary outcome of interest was the OS and recurrence-free survival (RFS) of patients who underwent LDLT at our center.
Interventions
- Procedure Liver transplantation
living donor liver transplantation
Primary outcome measures
- percentage of patients with recurrence free survival [Time frame: 5 years]
- percentage overall survival [Time frame: 5 years]
Eligibility criteria
Inclusion criteria
- Age ≥ 18
- Non-amenable to curative hepatic resection as defined by FLR <30%
- Histologically confirmed adenocarcinoma of the colon or rectum
- Candidate for LDLT for colorectal liver metastasis per the University of Rochester liver transplant program
Exclusion criteria
- Not a candidate of the LDLT liver transplant protocol for treatment of colorectal liver metastasis.
- Unwilling to consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
United States · 1 center
- University of Rochester Medical Center — Rochester
Identifiers
NCT: NCT05248581 · STUDY00004076