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Enrolling by invitation NCT05247255

Quadratus Lumborum Block for Total Hip Arthroplasty

Early Phase I Interventional Pain, Postoperative

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Active Comparator, Placebo Comparator.
Who it may be relevant to
Registry conditions: Pain, Postoperative. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Quadratus Lumborum (QL) Nerve Block for Patients Undergoing Primary Total Hip Arthroplasty (THA)

Overview

The quadratus lumborum (QL) block is a fascial plane block that has been described to provide analgesia from T7-L3 dermatomes. The investigators aim to evaluate the efficacy of QL blocks in patients undergoing primary total hip arthroplasty (THA).

Detailed description

Investigators will enroll subjects planned for primary THA and allocate them into receiving a QL block with either saline or ropivacaine. Primary outcome will be pain scores over the first 48 hours after surgery.

Interventions

  • Drug Active Comparator
    QL block with 0.25% ropivacaine
  • Drug Placebo Comparator
    QL block with saline

Primary outcome measures

  • Pain score [Time frame: Up to 48 hrs post op]
Secondary outcome measures (6)
  • Opioid usage [Time frame: Up to 48 hrs post op]
  • Time to first stand [Time frame: Up to 1 week post surgery]
  • Time to first ambulation [Time frame: Up to 1 week post surgery]
  • Ambulation distance [Time frame: Up to 1 week post surgery]
  • Length of hospital stay [Time frame: Until discharge from hospital, up to 1 week post surgery]
  • Patient satisfaction [Time frame: Until day of discharge from the hospital, up to 1 week post surgery]

Eligibility criteria

Inclusion criteria

  • Adult subjects undergoing elective primary total hip arthroplasty

Exclusion criteria

  • patients age < 18,
  • documented allergy to local anesthetic
  • presence of peripheral neuropathy
  • patients with current long term opioid use defined as receiving an opioid on most days in a 90 day period
  • patients with a contraindication to spinal and regional anesthesia such as coagulopathy or infection at the site of the regional technique.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Quadruple blind
Primary purpose
Prevention

Study locations

United States · 1 center
  • UCLA Medical Center, Santa Monica — Santa Monica

Identifiers

NCT: NCT05247255 · 21-001850

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗