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Recruiting NCT05242861

Retrospective Study of Brachytherapy

— Observational Brachytherapy Uterine Cervical Neoplasms Uterine Neoplasms Vulvar Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Brachytherapy.
Who it may be relevant to
Registry conditions: Brachytherapy, Uterine Cervical Neoplasms, Uterine Neoplasms, Vulvar Cancer. Basic parameters: 18 years — 80 years · Female.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
China
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

A Retrospective Study of Brachytherapy in Gynecological Cancers

Overview

Brachytherapy for gynecological cancers will be studied retrospectively.

Interventions

  • Radiation Brachytherapy
    Applicator, dose, schedule, technology, image, 3D print, efficacy, toxicity of brachytherapy

Primary outcome measures

  • Overall survival rate [Time frame: 5-year]
Secondary outcome measures (2)
  • Progression-free survival rate [Time frame: 5-year]
  • Side effects [Time frame: 5-year]

Eligibility criteria

Inclusion criteria

  • 18 - 80 female
  • Underwent brachytherapy
  • With gynecological cancer

Exclusion criteria

  • Refusal to enter this trial

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

China · 1 center
  • Zhejiang Cancer Hospital — Hangzhou

Publications

  • Sturdza A, Potter R, Fokdal LU, Haie-Meder C, Tan LT, Mazeron R, Petric P, Segedin B, Jurgenliemk-Schulz IM, Nomden C, Gillham C, McArdle O, Van Limbergen E, Janssen H, Hoskin P, Lowe G, Tharavichitkul E, Villafranca E, Mahantshetty U, Georg P, Kirchheiner K, Kirisits C, Tanderup K, Lindegaard JC. Image guided brachytherapy in locally advanced cervical cancer: Improved pelvic control and survival PMID 27134181
  • Lindegaard JC, Madsen ML, Traberg A, Meisner B, Nielsen SK, Tanderup K, Spejlborg H, Fokdal LU, Norrevang O. Individualised 3D printed vaginal template for MRI guided brachytherapy in locally advanced cervical cancer. Radiother Oncol. 2016 Jan;118(1):173-5. doi: 10.1016/j.radonc.2015.12.012. Epub 2015 Dec 29. PMID 26743833
  • Sekii S, Tsujino K, Kosaka K, Yamaguchi S, Kubota H, Matsumoto Y, Ota Y, Sasaki R, Soejima T. Inversely designed, 3D-printed personalized template-guided interstitial brachytherapy for vaginal tumors. J Contemp Brachytherapy. 2018 Oct;10(5):470-477. doi: 10.5114/jcb.2018.78832. Epub 2018 Oct 9. PMID 30479625
  • Harris BD, Nilsson S, Poole CM. A feasibility study for using ABS plastic and a low-cost 3D printer for patient-specific brachytherapy mould design. Australas Phys Eng Sci Med. 2015 Sep;38(3):399-412. doi: 10.1007/s13246-015-0356-3. Epub 2015 Jun 25. PMID 26108891
  • Han K, Milosevic M, Fyles A, Pintilie M, Viswanathan AN. Trends in the utilization of brachytherapy in cervical cancer in the United States. Int J Radiat Oncol Biol Phys. 2013 Sep 1;87(1):111-9. doi: 10.1016/j.ijrobp.2013.05.033. Epub 2013 Jul 9. PMID 23849695

Identifiers

NCT: NCT05242861 · BTOG 2201

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗