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Recruiting NCT05221450

Factors Affecting the Endodontic Treatment Outcome

— Observational Apical Periodontitis Apical Granuloma Apical Cyst

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: primary endodontic treatment.
Who it may be relevant to
Registry conditions: Apical Periodontitis, Apical Granuloma, Apical Cyst. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Slovenia
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

The aim of this prospective cohort observational study is: (i) to assess the endodontic treatment outcome in a private specialist endodontic office in Slovenia; (ii) to estimate the effect of various pre-, intra- and postoperative factors onto endodontic treatment outcome.

Interventions

  • Procedure primary endodontic treatment

Primary outcome measures

  • Treatment outcome based on strict combined radiographic and clinical criteria [Time frame: 1-4 years postoperatively]

Eligibility criteria

Inclusion criteria

  • patients referred to the private endodontic specialist office for endodontic treatment
  • written informed consent was obtained prior beginning of the treatment.

Exclusion criteria

  • preoperative advanced periodontal disease
  • prior microsurgical root-end resection performed
  • apices of the tooth were not clearly discernible on any of periapical radiographs
  • endodontic treated teeth were extracted for non-endodontic reason
  • the patient did not attend a follow-up examination.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Slovenia · 1 center
  • Odontos, specialistična zobna ambulanta, d.o.o. — Ljubljana

Publications

  • Ng YL, Mann V, Gulabivala K. A prospective study of the factors affecting outcomes of nonsurgical root canal treatment: part 1: periapical health. Int Endod J. 2011 Jul;44(7):583-609. doi: 10.1111/j.1365-2591.2011.01872.x. Epub 2011 Mar 2. PMID 21366626
  • Friedman S, Abitbol S, Lawrence HP. Treatment outcome in endodontics: the Toronto Study. Phase 1: initial treatment. J Endod. 2003 Dec;29(12):787-93. doi: 10.1097/00004770-200312000-00001. PMID 14686806
  • European Society of Endodontology. Quality guidelines for endodontic treatment: consensus report of the European Society of Endodontology. Int Endod J. 2006 Dec;39(12):921-30. doi: 10.1111/j.1365-2591.2006.01180.x. PMID 17180780
  • Ng YL, Mann V, Rahbaran S, Lewsey J, Gulabivala K. Outcome of primary root canal treatment: systematic review of the literature - part 1. Effects of study characteristics on probability of success. Int Endod J. 2007 Dec;40(12):921-39. doi: 10.1111/j.1365-2591.2007.01322.x. Epub 2007 Oct 10. PMID 17931389
  • Ng YL, Mann V, Rahbaran S, Lewsey J, Gulabivala K. Outcome of primary root canal treatment: systematic review of the literature -- Part 2. Influence of clinical factors. Int Endod J. 2008 Jan;41(1):6-31. doi: 10.1111/j.1365-2591.2007.01323.x. Epub 2007 Oct 10. PMID 17931388
  • Ricucci D, Russo J, Rutberg M, Burleson JA, Spangberg LS. A prospective cohort study of endodontic treatments of 1,369 root canals: results after 5 years. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Dec;112(6):825-42. doi: 10.1016/j.tripleo.2011.08.003. PMID 22099859

Identifiers

NCT: NCT05221450 · 0120-402/2019/5

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗