Language Acquisition in the Brain and Algorithms: Towards Systematic Monitoring of the Evolution of Semantic Representations in Biological and Artificial Neural Networks
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: intracranial brain recording.
- Who it may be relevant to
- Registry conditions: Language Acquisition in the Brain. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Speech depends on our ability to recursively combine successive words into a complex sense. Although the order of these putative operations (syntax) has been the subject of extensive examination in the way in which the human brain learns to perform a "Semantic composition" remains largely unknown. The Rothschild Hospital houses a unit specializing in drug-resistant epilepsy in children from 2 to 20 years old. The identification of the epileptogenic zone often requires making an iEEG recording for a week (implantation of intracerebral electrodes in depth). Sometimes this recording has to be repeated, providing a unique opportunity to directly record brain activity at different periods of its development. Children will listen to pre-recorded phrases and stories such as "The Little Prince of Antoine de Saint-Exupéry" while being recorded with iEEG.
Interventions
- Other intracranial brain recording
Any patient benefiting from a long-term intracranial brain recording.
Primary outcome measures
- This is a non-clinical research study investigating from intracranial recordings how speech representation changes throughout human development. [Time frame: maximum 21 days]
Eligibility criteria
Inclusion criteria
- Any patient benefiting from a long-term intracranial brain recording.
- Non-opposition to participating in the study (adult patients)
- Non-opposition of at least one of the holders of the exercise of parental authority (minor patients)
Exclusion criteria
- Patient with complete deafness
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 1 center
- Fondation Ophtalmologique de Rothschild — Paris
Identifiers
NCT: NCT05217043 · PBN_2021_25