ACUTE-Acute Surgical Care- Risk Factors and Outcomes for Patients in Need of Acute Surgical Care
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Observational study of different treatments and time to treatment.
- Who it may be relevant to
- Registry conditions: Risk Factors, Complication of Surgical Procedure, Complication of Treatment, Complication of Anesthesia. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Sweden
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Observational retrospective study of patients in need of acute surgical care admitted to Skåne University Hospital between 2009 and 2019.
Detailed description
At Skåne University Hospital approximately 6000 individuals are treated for acute abdominal diseases each year. Given the high number of patients, there is an urgent need to optimize acute surgical care. Lower complication rates would decrease hospital stay, health care costs as well as personal suffering.
Assessment instruments for risks and frailty are not validated for the acute setting and the investigators hypothesize there is room for improvement in prophylactic interventions and risk assessment. The investigators will study cohorts of patients with three different surgical diagnosis: acute pancreatitis, gastrointestinal bleeding and perforated ulcer aiming to identify risk factors for complications or death and to investigate assessment tools in this population. Using propensity score analysis, the investigators will try to identify treatment options associated with better outcome for subcohorts defined by frailty, comorbidity, age or gender. Specific factors of interest include: time to- and kind of treatment, handling of ongoing pharmacological therapy (anticoagulants, corticosteroids) and need for further treatments on a long time basis. The results from this project will be used in a future prospective study where prophylactic treatments and specific treatment options are studied.
Interventions
- Other Observational study of different treatments and time to treatment
Different treatment based on the clinical decision
Primary outcome measures
- Mortality [Time frame: 5 years]
- Reintervention [Time frame: 5 years]
- Recurrent disease [Time frame: 5 years]
Secondary outcome measures (3)
- Lengths of hospital stay [Time frame: 5 years]
- Number of interventions [Time frame: 5 years]
- complications [Time frame: 5 years]
Eligibility criteria
Inclusion Criteria: Patients admitted to Skåne University hospital in need of acute surgical care -
Exclusion Criteria: Below 18 years old
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Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
Sweden · 1 center
- Skåne University Hospital — Malmö
Publications
- Forsberg-Puckett A, Wurm Johansson G, Regner S. Presentation of gastrointestinal bleeding in patients with antithrombotic therapy, results from a consecutive retrospective cohort. Scand J Trauma Resusc Emerg Med. 2025 Sep 10;33(1):146. doi: 10.1186/s13049-025-01431-1. PMID 40931336
Identifiers
NCT: NCT05195697 · 2019-03583