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Recruiting NCT05100940

Progress Complication

Observational Coronary Artery Disease

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Cardiac Catheterization.
Who it may be relevant to
Registry conditions: Coronary Artery Disease. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Prospective Global Registry of Complications of Percutaneous Coronary Interventions

Overview

Coronary angiography and percutaneous coronary intervention (PCI) is often performed in patients with ischemic heart disease. The safety of PCI has improved with new devices and strategies, but complications still occur, especially during complex procedures. The objectives of this multi-center observational registry are to examine frequency of complications occuring during cardiac catheterization and PCI, examine procedural strategies utilized for complication management, and evaluate the clinical outcomes (both immediate and during follow-up.)

Detailed description

The safety of PCI has improved with new devices and strategies, but complications still occur, especially during complex procedures. Systematic study of cardiac procedure complications can improve procedural safety and optimize short and long-term patient outcomes. The objectives of this multi-center observational registry are to

1-Examine the frequency and types of complications occurring during cardiac catheterization and PCI among participating sites, 2-Examine the procedural strategies (techniques and devices) utilized for complication management, 3-Evaluate the clinical outcomes (both immediate and during follow-up) after each complication type.

Interventions

  • Procedure Cardiac Catheterization
    Cardiac Catheterization

Primary outcome measures

  • in-hospital major cardiac adverse events (MACE) [Time frame: From Date of Procedure to Date of Hospital Discharge, approximately 48-72 hrs after index procedure]
  • Technical Success of PCI [Time frame: From Date of Procedure to Date of Hospital Discharge, approximately 48-72 hrs after index procedure]
  • Procedural success of PCI [Time frame: From Date of Procedure to Date of Hospital Discharge, approximately 48-72 hrs after index procedure]

Eligibility criteria

  • Over 18 years of age
  • undergoing coronary angiography or PCI
  • A complication occurred during or after the procedure

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Case-only

Study locations

United States · 1 center
  • Minneapolis Heart Institute Foundation — Minneapolis

Publications

  • Mutlu D, Ser OS, Strepkos D, Carvalho PE, Alexandrou M, Kladou E, Mastrodemos O, Rangan BV, Sara JDS, Jalli S, Voudris K, Sandoval Y, Nicholas Burke M, Brilakis ES. Acute Kidney Injury Requiring Dialysis Following Percutaneous Coronary Intervention: Insights From the PROGRESS-COMPLICATIONS Registry. Catheter Cardiovasc Interv. 2025 Sep;106(3):1883-1891. doi: 10.1002/ccd.70012. Epub 2025 Jul 17. PMID 40676818

Identifiers

NCT: NCT05100940 · PROGRESS-COMPLICATION

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗