A Multi-Center Data System and Collaborative Network in China for Severe Infection and Sepsis Children
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Not applicable（Cohort study）.
- Who it may be relevant to
- Registry conditions: Critical Illness, Severe Sepsis. Basic parameters: 29 Days — 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- China
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Establishment of a Multi-Center Big Data System for Severe Infection and a Collaborative Network on Sepsis in Chinese Children
Overview
1\. To research the current situation of severe infection in children in China, and to investigate the incidence, prognosis and disease burden of severe infection in children in different regions of China. 2. Establish the risk prediction model and diagnosi model of severe infection in children, and verify the accuracy of the model in multi-center; 3. To study the effectiveness and safety of different treatments in real diagnosis and treatment, and to evaluate the efficacy of subgroups under different ages and high risk factors.
Detailed description
1.Children between 0 and 18 years old. 2.Severe pneumonia and/or sepsis.Patients were included who meet the guidline for diagnosis and treatment of community-acquired pneumonia in Children (2019) issued by the National Health Commission of the people's Republic of China and/or who meet the International Guide to the 2020 campaign to Save sepsis: management of septic shock and sepsis-related organ dysfunction in children. 3.notifiable infectious diseases.4.The researcher believes that he is not suitable to participate in other situations in this study.5.Participants in other clinical trials in the same period.
Interventions
- Other Not applicable（Cohort study）
This is a prospective observational study and does not include interventions.
Primary outcome measures
- survival rate [Time frame: within 28 days after they discharged from PICU]
Secondary outcome measures (1)
- length of stay in PICU [Time frame: within 28 days after they discharged from PICU]
Eligibility criteria
Inclusion criteria
- Children between 0 and 18 years old.
- Severe pneumonia and/or sepsis.
Exclusion criteria
- notifiable infectious diseases.
- The researcher believes that he is not suitable to participate in other situations in this study.
- Participants in other clinical trials in the same period.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
China · 1 center
- Children's Hospital of Fudan University — Shanghai
Identifiers
NCT: NCT04955210 · fdpicu-18