Prevent Cancer- Greenville
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cancer, High-Risk Cancer. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Prevent Cancer-Greenville: A Center for Cancer Prevention and Wellness Research Project
Overview
Prevent Cancer-Greenville was created to provide individuals with the opportunity to have their risk of developing cancer studied. Some individuals may be at a higher risk due to their personal lifestyle, family history and/or exposures. If subjects are found to be at high risk for developing a disease, they will be sent to a healthcare provider for further care.
Detailed description
Participants' personal history, lifestyle behaviors and blood, urine, and cheek swab specimens will be used to detect changes or trends that might put them at risk for developing cancer. Some individuals may be at an above average risk of cancer due to lifestyle, family background, personal genetic makeup, or environmental exposures. This will be determined by a process called risk stratification. Risk stratification involves looking at all health-related aspects of a person, determining their individualized risk through screening, and educating them on measures to reduce potential for disease. Participants will complete a yearly health assessment which includes measurements for nutrition, activity, individual risk factors and body composition, including weight height and a special scale which measures fluid and fat.
Primary outcome measures
- Assess changes in nutrition by nutrition questionnaire [Time frame: Yearly follow up for 10 years]
- Assess changes in physical activity by physical activity questionnaire [Time frame: Yearly follow up for 10 years]
- Assess changes in smoking habits [Time frame: Yearly follow up for 10 years]
- Assess changes in alcohol use [Time frame: Yearly follow up for 10 years]
- Assess hereditary risk through family history review [Time frame: Yearly follow up for 10 years]
- Assess lifetime breast cancer risk through the Tyrer-Cuzick version 8 breast risk evaluation tool [Time frame: Yearly follow up for 10 years]
- Assess 5- year breast cancer risk through the GAIL breast risk evaluation tool [Time frame: Yearly follow up for 10 years]
- Early detection of malignancies through screening [Time frame: Yearly follow up for 10 years]
- Assess changes in fat mass by SOZO measurements [Time frame: Yearly follow up for 10 years]
- Assess changes in muscle mass by SOZO measurements [Time frame: Yearly follow up for 10 years]
Secondary outcome measures (1)
- Assess changes in quality of life by the 5-level EuroQol-5D version (EQ-5D-5L) questionnaire [Time frame: Yearly follow up for 10 years]
Eligibility criteria
Inclusion criteria
- 18 years or older
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Ecologic or community
Study locations
United States · 1 center
- Prisma Health-Upstate — Greenville
Identifiers
NCT: NCT04947098 · Pro00077309