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Recruiting NCT04861051

Understanding Ketamine's Dissociative Effects (KD Study)

Phase I Interventional Epilepsy

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Ketamine.
Who it may be relevant to
Registry conditions: Epilepsy. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Understanding Ketamine's Dissociative Effects in Epilepsy (KD Study)

Overview

The purpose of this study is to understand how ketamine brings about dissociative symptoms.

Detailed description

The goal of this proposed research is to record the effects of ketamine on brain activity to understand the changes that occur during dissociation in epilepsy patients with stereoEEG.

Interventions

  • Drug Ketamine
    Study participants will receive 0.5mg/kg of ketamine - one single infusion

Primary outcome measures

  • Number of participants with dissociative events during ketamine infusion as assessed by CADSS (Clinician-Administered Dissociative State Scale) [Time frame: up to 1 week]

Eligibility criteria

Inclusion criteria

  • Patient in Stanford Epilepsy Monitoring Unit
  • Age >18 years old.

Exclusion criteria

  • Lifetime psychotic or bipolar disorder
  • Inability to speak, read or understand English
  • Pregnant or nursing females
  • Prior adverse ketamine response

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
N/A
Model
Single group
Masking
Open label
Primary purpose
Basic science

Study locations

United States · 1 center
  • Stanford University School of Medicine — Palo Alto

Identifiers

NCT: NCT04861051 · 60085

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗