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Recruiting NCT04829526

Firm Observational Clinical Unicenter Study on Guillain Barré Syndrome

— Observational Guillain-Barre Syndrome (GBS)

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: data collection.
Who it may be relevant to
Registry conditions: Guillain-Barre Syndrome (GBS). Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Switzerland
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Firm Observational Clinical Unicenter Study on Guillain Barré Syndrome (FOCUS on GBS)

Overview

The aim of this retrospective observational single-center cohort study is to gain a deeper understanding regarding the frequency, the clinical and electrophysiologic characteristics (e.g., the diagnostic work up), complications, treatment regimes, and their associations with specific courses of disease and outcomes in adult patients with the suspected or proven diagnosis of GBS.

Detailed description

Guillain Barré Syndrome (GBS) is a rare and life-threatening neurological emergency. The aim of this retrospective study including adult GBS patients from the last 15 years treated at the University Hospital of Basel is to assess data regarding diagnostic workup, treatment, clinical course including complications and outcomes.

Interventions

  • Other data collection
    Retrospective extraction of demographic, clinical, laboratory, and electrophysiological data from the digital medical records

Primary outcome measures

  • frequency of GBS [Time frame: one time retrospective assessment at baseline]
  • clinical characteristics of GBS [Time frame: one time retrospective assessment at baseline]
  • electrophysiologic characteristics of GBS [Time frame: one time retrospective assessment at baseline]
  • complications of GBS [Time frame: one time retrospective assessment at baseline]
  • treatment regimes of GBS [Time frame: one time retrospective assessment at baseline]
  • outcomes of GBS [Time frame: one time retrospective assessment at baseline]

Eligibility criteria

Inclusion criteria

  • suspected diagnosis of GBS, who have been treated at the University Hospital of Basel from 01.01.2005-28.02.2021

Exclusion criteria

  • Patients with documented refusal of the general consent.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Observational model
Cohort

Study locations

Switzerland · 1 center
  • Clinic for Intensive Care Medicine; University Hospital Basel — Basel

Identifiers

NCT: NCT04829526 · 2021-00402; ko21Sutter

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗