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Recruiting NCT04766177

Role of Bumetanide in Treatment of Autism

Phase III Interventional Autism

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Bumetanide, Placebo.
Who it may be relevant to
Registry conditions: Autism. Basic parameters: 3 years — 12 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
Egypt
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Role of Bumetanide in Treatment of Autism Spectrum Disorder in Children

Overview

Role of bumetanide in Autism

Detailed description

Role of Bumetanide in Treatment of Autism spectrum disorder in children

Interventions

  • Drug Bumetanide
    bumetanide 0.5 mg twice daily
  • Drug Placebo
    placebo tablets twice daily

Primary outcome measures

  • Number of patients with improved CARS score [Time frame: 6 months]

Eligibility criteria

Inclusion criteria

  • All patients with ASD diagnosed by CARS rating Scale⩾30.
  • Age of patients range between (3-12) years.

Exclusion criteria

  • Patients with ASD associated with neurological antecedents (including epilepsies and febrile seizures), hepatic, renal dysfunction or electrocardiogram abnormalities and syndromatic children(Rett).

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Parallel assignment
Masking
Quadruple blind
Primary purpose
Treatment

Study locations

Egypt · 1 center
  • Sherief Abd-Elsalam — Tanta

Identifiers

NCT: NCT04766177 · autism

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗