Local Tranexamic Acid During Vaginal Hysteractomy to Reduce Blood Loss
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: local tranexamic acid injection, local normal saline injection to cervix.
- Who it may be relevant to
- Registry conditions: Blood Loss. Basic parameters: 20 years — 90 years · Female.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Israel
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Local Tranexamic Acid During Vaginal Hysterectomy to Reduce Blood Loss
Overview
Assessing the efficiency of Prophylactic use of local tranexamic acid during vaginal hysterectomy to reduce blood loss during operation
Detailed description
This randomized control trial will investigate whether local tranexamic acid is efficient for decreasing bleeding during vaginal hysterectomy.
The investigators will randomize local placebo (saline) vs. local 1 gr tranexamic acid; local 1gr tranexamic acid diluted in 10 ml saline and local 10 ml saline at the beginning of surgery.
Interventions
- Drug local tranexamic acid injection
local tranexamic acid injection to cervix- 1 g tranexamic acid diluted in 10 ml saline - Other local normal saline injection to cervix
local normal saline injection to the cervix- 20 ml saline
Primary outcome measures
- Blood loss during operation - measure in ml [Time frame: End of surgery]
Eligibility criteria
Inclusion criteria
- 20-90 years old female patients going through vaginal hysterctomy
Exclusion criteria
- massive bleeding during operation due to major vessles injury
- known coagulopathies
- sensitivity to tranexamic acid
- medical need in tranexamic acid administration during operation due to bleeding
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Allocation
- Randomized
- Model
- Single group
- Masking
- Double blind
- Primary purpose
- Prevention
Study locations
Israel · 2 centers
- Meir Medical Center — Kfar Saba
- Meir medical center — Kfar Saba
Identifiers
NCT: NCT04760301 · 0354-19-MMC