Analysis of Motor Skills in Subjects Aged 55 and Over: the Role of Cognitive Abilities for Planning Movement.
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Sequence 1, Sequence 2, Sequence 3.
- Who it may be relevant to
- Registry conditions: Mild Cognitive Disorder. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
Falling is an event that is more frequent and severe in older age. It can lead to a loss of autonomy and a decrease in quality of life. It is therefore important to understand this phenomenon in order to better prevent it. Among the multiple risk factors associated with falling, recent research has shown a link between the decline in cognitive abilities (i.e., the mental processes that form our knowledge, such as memory) and the risk of falling. However, the impact of this cognitive decline on motor skills is still poorly understood. The purpose of this research is to study how the changes induced by aging affect motor skills. This would make it possible to take a new look at the phenomenon of falls occurring in the elderly and, in the long term, to improve the prevention and rehabilitation.
Interventions
- Other Sequence 1
perform arm movements towards a target - Other Sequence 2
judge the verticality of an object - Other Sequence 3
In standing position, point as quickly as possible with the right arm at the diode that will light up in front of the participant.
Primary outcome measures
- Sequence 1: symmetry ratio of the finger speed profile [Time frame: through study completion, an average of 3 years]
- Sequence 2 : perception bias (error in degrees of angle) of dynamic subjective visual vericality [Time frame: through study completion, an average of 3 years]
- Sequence 3 : activation time of the focal muscles in relation to the postural muscles [Time frame: through study completion, an average of 3 years]
Eligibility criteria
Inclusion criteria
- Neurotypical subjects group:
- Person aged 18 to 40 years
- Person who has given oral consent
- Affiliated to national health insurance
- Right-handed person
- Group of elderly neurotypical subjects:
- Person over 55 years of age
- Person who has given oral consent
- Affiliated to national health insurance
- No cognitive problems (MMSE score >26)
- Right-handed person
- Elderly mild cognitive disorder subject group:
- Person over 55 years of age
- Person who has given oral consent
- Diagnosis of Mild Cognitive Disorder made by a neurologist at the Centre Mémoire Ressources et Recherche (CMRR) of the University Hospital of Dijon, following the recommendations of the National Institute for Aging and Alzheimer's Association (Albert et al., 2011) This diagnosis is based on psychometric tests, brain imaging and the evolution of cognitive disorders, including an MMSE test.
- Right-handed person
Exclusion criteria
- Neurological or psychiatric history with the exception of the TCL group.
- Follow-up of drug treatment in the last three months that may affect cognitive and/or motor skills.
- Received a shoulder prosthesis on the dominant side.
- Received a hip and/or knee replacement less than a year ago.
- Disabling joint disease of the hip or knee shoulder
- Protected adults (curatorship, guardianship)
- Person deprived of their liberty b judicial or administrative decision
- Pregnant, parturient or breastfeeding woman
- Major unable to consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Case-control
Study locations
France · 1 center
- Chu Dijon Bourgogne — Dijon
Identifiers
NCT: NCT04754906 · MANCKOUNDIA 2018