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Recruiting NCT04687865

Constitution of a Biobank for Studies Related to Organ Transplantation (Lyon Centaure Biocollection)

— Observational Organ Transplantation

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Biobank.
Who it may be relevant to
Registry conditions: Organ Transplantation. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Official title

Biological Material Bank for Studies Related to Organ Transplantation

Overview

This study aims to constitute a collection of biological materials from in transplant patients and to provide biological materials from transplanted patients in order : i) validate new theory on the cause of allograft loss, ii) develop innovative biomarker for rejection and other transplantation-related conditions (such as BK virus nephropathy, Post-transplant lymphoproliferative disorder ( PTLD) ...)

Interventions

  • Other Biobank
    For each patient included in the study the following samples will be collected at the indicated time points after transplantation: * Serum samples and plasma sample: Day1, Month 1, Month 3, Month 6, Month 12, month 60, month 120 and at the time of each allograft biopsy. * Urines samples: Month 3 and Month 12 and at the time of each allograft biopsy. * Peripheral Blood Mononuclear Cell (PBMC): for each organ allograft biopsy. * Allograft biopsies: systematically at Month 3, and Month 12, and for

Primary outcome measures

  • the biological samples [Time frame: At inclusion]
  • Change Biological Samples [Time frame: Month 1]
  • Change Biological Samples [Time frame: Month 3]
  • Change Biological Samples [Time frame: Month 6]
  • Change Biological Samples [Time frame: Month 12]
  • Change Biological Samples [Time frame: Month 60]
  • Change Biological Samples [Time frame: Month 120]

Eligibility criteria

Inclusion criteria

  • Male or Female patient ≥18 years old
  • Recipient of an organ transplant
  • Written informed consent

Exclusion criteria

  • Non-affiliation to a social security system.
  • Subjects deprived of liberties
  • Pregnant or breastfeeding woman

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Cohort

Study locations

France · 1 center
  • Hopital Edouard Herriot — Lyon

Identifiers

NCT: NCT04687865 · 69HCL20_0964

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗