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Recruiting NCT04674267

Resilience and Equity in Aging, Cancer, and Health (REACH)

No phase Interventional Gastric Cancer Colon Cancer Esophageal Cancer Rectal Cancer

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: Phase 2 Intervention - Geriatric Co-Management.
Who it may be relevant to
Registry conditions: Gastric Cancer, Colon Cancer, Esophageal Cancer, Rectal Cancer. Basic parameters: from 70 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
United States
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Official title

Resilience and Equity in Aging, Cancer, and Health (REACH): Promoting Physical Resilience and Cancer Care Equity for Adults Age 70 and Older Diagnosed With Gastrointestinal Malignancy

Overview

The purpose of this multi-phase research study is to understand how consultation of cancer care with a geriatrician can best improve outcomes for older adults with gastrointestinal malignancies.

Detailed description

This research study will be conducted in three phases:

* Phase 1 - Needs assessment and implementation plan * Phase 2 - Pilot Intervention * Phase 3 - Expanded Clinical Trial

* Please note Phase 2 - Pilot Intervention and Phase 3 - Expanded Clinical Trial will be added to the clinicaltrials.gov record once Institutional Review Board (IRB) approved.

Phase 1 is composed of three aims and will inform the subsequent two phases:.

* Aim 1: To evaluate the perceived needs of Older Adults diagnosed with gastrointestinal malignancies, caregivers, staff, and faculty to characterize the implementation setting for a geriatric consultation. * Aim 2: To refine the proposed REACH program implementation plan based on qualitative feedback provided by Older Adult (OA) patients, their identified caregivers, staff, and faculty. * Aim 3: Determine the patient, demographic, social determinants, clinical and disease characteristics of Older Adults (OA) associated with ED visits/hospitalization following initial oncology consultation at DF/BWCC in year 2019. * Phase 2 intervention has started as of January 2022 following IRB approval. Study team has begun recruiting participants into Phase 2 intervention of REACH study starting in January 2022. Participants approached by REACH coordinator for consenting and enrollment after their initial consult visit at Dana-Farber/Brigham and Women's Cancer Center (DF/BWCC). Participants are then asked to complete an electronic fitness assessment (EFA) that is sent to them via Patient Gateway. Participants complete this questionnaire and receive a score of "Robust", "Pre-frail", or "Frail" - those who score "Pre-frail" or "Frail" will be randomized to meet with a study geriatrician for geriatric co-management intervention alongside their standard oncology care. All enrolled participants will be followed for a duration of 1 year as they are continuing care at DF/BWCC.

Interventions

  • Other Phase 2 Intervention - Geriatric Co-Management
    Participants will complete an electronic fitness assessment questionnaire - once completed, they will receive a score of "Robust", "Pre-Frail" or "Frail". Those who are "Pre-frail" or "Frail" will be randomized to meet with a study geriatrician for geriatric co-management in addition to usual oncology care. All participants will be followed for a duration of 1 year.

Primary outcome measures

  • Feasibility of electronic fitness assessment questionnaire (developed from Comprehensive Geriatric Assessment tool) [Time frame: 1 year]
  • Acceptability of electronic fitness assessment questionnaire [Time frame: 1 year]
  • Association of geriatric consultation with number of unplanned ED visits/hospitalizations among older adult participants [Time frame: 1 year]

Eligibility criteria

Inclusion criteria

  • Patients who are age 70+ at time of initial consult at DF/BWCC
  • Diagnosed with a gastrointestinal cancer, including: cancers of the esophagus, stomach, pancreas, liver, bile duct, ampulla, colon, rectum, or anus, as well as neuroendocrine tumors.
  • Continuing care at DF/BWCC beyond initial consult visit
  • English and Spanish-speaking

Exclusion criteria

  • Patients less than age 70 at time of initial consultation appointment with DF/BWCC.
  • Patients who are not continuing care at DF/BWCC beyond first consult visit.
  • Not proficient in English or Spanish
  • Patient who are not considered appropriate for enrollment due to complex medical, social, or other situation as determined by their primary oncology team.
  • Participants with psychiatric illness/social situations that would limit compliance with study requirements.

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Healthy volunteers: No

Study design

Allocation
Randomized
Model
Single group
Masking
Open label
Primary purpose
Health services research

Study locations

United States · 1 center
  • Dana-Farber Cancer Institute — Boston

Identifiers

NCT: NCT04674267 · 20-275

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗