Recruiting NCT04659824
Study of Iron Accumulation Measured in MRI in Non-pathological Aging
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Healthy Aging. Basic parameters: 18 years — 95 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
To study the correlation between the iron load in brain, measured in MRI, and the age of healthy subjects Secondary objectives are to study the correlations between the iron load in cortical brain regions and (i) the cognitive performances, (ii) markers of aging (MRI, EEG, OCT, biology),and (iii) demographical factors involved in iron load.
Primary outcome measures
- Correlation coefficient between iron load in MRI and age [Time frame: baseline]
Eligibility criteria
Inclusion criteria
- Men or women between 18 and 95 years old
- French speaker with capability to understand the instructions
- Health insurance
Exclusion criteria
- Pregnancy
- minor subject
- no informed consent agreement
- subject enrolled in pharmaceutic study or exclusion period
- MRI contra-indications
- Neurological or psychiatric disorders
- MOCA < 26
- Psychotropic drugs
- More than 3 MRI exams
- More than 1 neuropsychological assessment (same cognitive tests) in the last 12 months
- Unable to follow the entire protocol according to the investigator
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
France · 1 center
- Hopital Roger Salengro, CHU Lille — Lille
Identifiers
NCT: NCT04659824 · 2019_24 · 2020-A00491-38