Recruiting NCT04658290
Prevalence of Obstructive Sleep Apnea (OSA) and the Association With Cognitive Impairment
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Obstructive Sleep Apnea, Cognitive Impairment. Basic parameters: 40 years — 74 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Hong Kong
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Overview
The study is aimed to carry out an epidemiology study investigating the prevalence of obstructive sleep apnea (OSA) and the association with cognitive impairment.
Primary outcome measures
- Number of subjects having apnea-hypopnea index of more than 5 [Time frame: 1 year]
Secondary outcome measures (2)
- incidence of cerebrovascular disease [Time frame: 5 years]
- Montreal Cognitive Assessment [Time frame: 5 years]
Eligibility criteria
Inclusion criteria
- Have stability of at least 4 weeks on permitted medications (i.e. medications known not to affect sleep architecture or circadian rhythms).
Exclusion criteria
- Suspected dementia or a score of <24 on the mini-mental state examination
- A diagnosis of neurological disorders (e.g. Parkinson's Disease, Epilepsy, Multiple Sclerosis)
- Psychiatric disorders including current major depression; bipolar disorder; schizophrenia
- Other known clinically significant sleep disorders (e.g. narcolepsy)
- Been currently receiving CPAP or bi-level pressure for OSA
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: Yes
Study design
- Observational model
- Cohort
Study locations
Hong Kong · 1 center
- Chinese University of Hong — Hong Kong
Identifiers
NCT: NCT04658290 · SleepBrain_2019