Prognosis Factors for the Treatment of Pectus Carinatum With a Dynamic Compression System
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: dynamic compression system.
- Who it may be relevant to
- Registry conditions: Pectus Carinatum. Basic parameters: 6 years — 40 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
Pectus carinatum is a deformation of the thoracic wall causing an aesthetic prejudice. Since 2011, our team uses a dynamic compression system to treat this deformation. It is a harness that the patient wears all day long for an average duration of 1 year, and that remodels the chest by exerting a moderate pressure on it. The local cohort is one of the largest in the world. The few previous publications have shown the validity of this method, but the prognosis factors for success of this innovative treatment are not yet identified.
Detailed description
The principal insvestigator hypothesizes that the success or failure of the treatment depends on several parameters assessable before treatment, such as the patient's age, gender, initial correction pressure, symmetry or not of the deformation.
Interventions
- Other dynamic compression system
It is a harness that the patient wears all day long for an average duration of 1 year, and that remodels the chest by exerting a moderate pressure on it
Primary outcome measures
- Decrease of the deformation of more than 50% (measured in mm) after 6 months of treatment [Time frame: After 6 months of treatment]
Secondary outcome measures (1)
- Failure of treatment assessed by the patient, ie if the patients considers the treatment to have failed, if he choose to underwent surgery afterwards, or if he considered the pectus carinatum to have relapsed [Time frame: After the end of treatment (6 months to 2 years)]
Eligibility criteria
Inclusion criteria
- Patient who received proper information about the study.
- Patient with clinically diagnosed pectus carinatum.
- Treated at Saint-Etienne University Hospital using a dynamic compression system.
- Between October 2011 and January 2020 for the retrospective part, then between January 2020 and January 2022 for the validation cohort.
- With more than 6 months of follow-up since the beginning of the treatment.
Exclusion criteria
\-
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 1 center
- CHU de Saint-Etienne — Saint-Etienne
Publications
- Kieffer De Marco L, Filaire L, Vermersch S, Chapelle C, Garcin A, Tiffet O, Scalabre A. Prognostic Factors for Pectus Carinatum Treated by Dynamic Compression System: PECTUSDYN Trial. Eur J Cardiothorac Surg. 2026 Jan 6;68(1):ezaf444. doi: 10.1093/ejcts/ezaf444. PMID 41390917
Identifiers
NCT: NCT04452721 · 20CH030