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Recruiting NCT04451265

Diagnostic Accuracy of Optimized Diffusion-Weighted Imaging for Detecting Anterior Ischemic Optic Neuropathy

— Observational Neuro-Ophthalmology

For patients and families

In plain language

An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.

What is being studied
The protocol lists: MRI.
Who it may be relevant to
Registry conditions: Neuro-Ophthalmology. Basic parameters: from 18 years · All.
What needs checking
Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
Where it takes place
France
Next step
Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →

Unsure about the terms? Read our patient guide →

Overview

The patient presents to the ophthalmological emergencies and / or to the internal medicine department. NOIA clinical discovery Patient referred in radiology for brain and visual MRI. The two sequences added by the research (8 minutes) will be added to that of the treatment.

Interventions

  • Other MRI
    Diffusion sequence (8 minutes long) added to the initial MRI

Primary outcome measures

  • Study the sensitivity of the High resolution Diffusion sequence in the detection of NOIA, evaluated by a DWI hypersignal and an ADC hyposignal of the optic nerve [Time frame: basline]

Eligibility criteria

Inclusion criteria

  • Patient over 18 years old
  • Patient with suspected NOIA, evoked after clinical examination by a specialized ophthalmologist
  • For which a brain and visual MRI is planned
  • Express consent to participate in the study
  • Affiliate or beneficiary of a Social Security scheme

Exclusion criteria

  • Contraindication to MRI (electrical device, metallic foreign body, claustrophobia)
  • Patient benefiting from a legal protection measure
  • Pregnant or breastfeeding woman

Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.

Study design

Observational model
Case-only

Study locations

France · 3 centers
  • CHU de LILLE — Lille
  • Fondation A De Rothschild — Paris
  • Chu Rouen — Rouen

Identifiers

NCT: NCT04451265 · GPN_2020_6

Primary sources (government registries)

View this study on ClinicalTrials.gov ↗