Novel Imaging Techniques for the Characterization of Musculoskeletal Tumors II
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: MR imaging.
- Who it may be relevant to
- Registry conditions: Soft Tissue Neoplasm, Bone Neoplasm. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Novel Imaging Techniques for the Characterization of Musculoskeletal Tumors II: Texture Analysis and Artificial Intelligence
Overview
This study aims at evaluating the value of various artificial intelligence based techniques to improve the characterization and image post-processing for patients with musculoskeletal tumors.
Detailed description
Comparison of values relating to the texture parameters of tumors evaluated by MRI and ultra-high resolution CT between benign and malignant lesions using histological analysis as the standard of reference.
Comparison of the diagnostic performance of texture parameters derived from different MRI sequences and ultra-high resolution CT for musculoskeletal tumor characterization.
Evaluate the impact of ultra-high resolution with respect to standard resolution on CT images Comparison of the diagnostic performance of the texture parameters for the tumor on the diagnostic performance of texture analysis derived parameters for the characterization of musculoskeletal tumors.
Evaluate the effectiveness and accuracy of automatic artificial intelligence (AI) based tumor segmentation tools.
Evaluate the use of trabecular analysis on ultra-high resolution CT images for the evaluation of tumor-bone interfaces.
Interventions
- Diagnostic test MR imaging
Medical imaging
Primary outcome measures
- Lesion benignancy or malignancy [Time frame: Performed up to 6 months after CT and Magnetic Resonance (MR) imaging]
Secondary outcome measures (1)
- Sarcoma FNCLCC (fédération Nationale des Centres de Lutte Contre le Cancer) grade [Time frame: Performed up to 1 year after CT and MR imaging]
Eligibility criteria
Inclusion criteria
- Patients suspected to have a bone or soft-tissue tumor referred for imaging for initial tumors characterization and staging.
Exclusion criteria
- Pregnancy
- Breast feeding patients
- Renal insufficiency
- Contra indications to MRI or CT
- Prior surgery or treatment to the evaluated lesion.
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
France · 1 center
- CHU-Nancy — Nancy
Identifiers
NCT: NCT04394052 · 2019PI253