Biorepository to Support Research in Kidney Diseases
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Acute Kidney Injury, Acute Interstitial Nephritis, Kidney Diseases. Basic parameters: 18 years — 99 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- United States
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Overview
To support advances in the understanding of pathophysiology and therapies of kidney diseases by creating a BioBank of kidney tissue, DNA, plasma, and urine from patients with kidney diseases.
Detailed description
A biorepository of human samples to support research to advance understanding of human kidney diseases will be created. Clinically, kidney diseases are detected by blood and urine laboratory tests. However, the underlying cause of kidney disease is often not clear on blood and urine tests. In such cases, a clinician may choose to perform a kidney biopsy to establish the diagnosis. Patients who are scheduled to undergo a kidney biopsy will be invited to participate in this proposed study.
Primary outcome measures
- Histological diagnosis [Time frame: 5 years]
Secondary outcome measures (1)
- Occurrence of chronic kidney disease, end stage kidney disease or death [Time frame: 10 years]
Eligibility criteria
Inclusion criteria
- Patients scheduled to undergo a clinically indicated kidney biopsy
- English or Spanish speaking
Exclusion criteria
- Under 18 years or age
- Known pregnancy
- Additional vulnerable individuals (incarcerated, institutionalized, or otherwise unable to participate in the study)
- Inability to provide informed consent
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Other
Study locations
United States · 2 centers
- Yale New Haven Hospital, York Street Campus — New Haven
- Yale New Haven Hospital Saint Raphael Campus — New Haven
Identifiers
NCT: NCT04343417 · 2000027890 · 1K23DK117065-01A1 · R01DK128087