Cohort of Patients With Hepatocellular Carcinoma or Cholangiocarcinoma
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Cholangiocarcinoma, Hepatocellular Carcinoma. Basic parameters: from 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- France
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
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Official title
Cohort Study of Patients With Primary Hepatocellular Carcinoma or Cholangiocarcinoma
Overview
The main objective is to describe the evolution of patients treated for a primary malignant hepatobiliary tumor (hepatocellular carcinoma or cholangiocarcinoma) over the long course.
Detailed description
The collection of data from patients with CHC and cholangiocarcinomas who are cancers with poor prognosis is a major challenge to improve patients'care (diagnosis, prognosis); facilitate the search for new therapeutic targets and the follow-up of clinical studies; and develop personalized treatments.
Primary outcome measures
- Overall survival [Time frame: 5 years]
Secondary outcome measures (3)
- Overall survival [Time frame: 5 years]
- Disease free survival [Time frame: 2 and 5 years]
- Progression time under chemotherapy [Time frame: Time of progression under chemotherapy up to 5 years]
Eligibility criteria
Inclusion criteria
Inclusion criteria
- Age ≥ 18 years olds
- Medical care in Nephrology department since 2015
Cholangiocarcinoma:
\- Histologically and cytologically documented cholangiocarcinoma, regardless of the stage of the disease
Hepatocellular carcinoma:
- Hepatocellular carcinoma at any stage of the disease, presenting the diagnostic criteria according to the diagnostic criteria of Barcelona : Tumor of more than 1 cm, developed on cirrhosis liver with arterial phase hyperenhancement and washout in the portal venous or delayed phases on CT and MRI
- Hepatocellular histologically documented
Exclusion criteria
\- Lack of patient non-opposition
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
France · 1 center
- Serviec hépatologie-Hôpital Saint Antoine — Paris
Identifiers
NCT: NCT04340986 · APHP190473 · IDRCB 2019-A01679-48