Allergen Provocations- HCA Children's Hospital
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- The protocol lists: Oral provocation test.
- Who it may be relevant to
- Registry conditions: Allergy in Children. Basic parameters: 0 years — 18 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Denmark
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Allergen Provocations at Hans Christian Andersen Children's Hospital
Overview
A prospective study of all allergen provocations performed in children at the Hans Christian Andersen Children's Hospital.
Detailed description
The purpose of the study is to investigate the impact of co-morbidities, history, and allergen tests on the outcome of allergen provocation tests.
Subjects are children aged 0-18 years old investigated for allergy to foods or antibiotics. Data entered in the database are demographics, co-morbidities, symptoms, SPT, specific IgE and details of the allergen provocations.
Interventions
- Diagnostic test Oral provocation test
Titrated provocation with allergen
Primary outcome measures
- The association of allergy tests with the result of allergen provocation [Time frame: 5 years]
Eligibility criteria
Inclusion criteria
clinical suspicion of allergy to foods or antibiotics informed concent -
Exclusion criteria
\-
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Healthy volunteers: No
Study design
- Observational model
- Cohort
Study locations
Denmark · 1 center
- Hans Christian Andersen Children's Hospital — Odense
Publications
- Gradman J, Petersen BT, Halken S. Oral food challenge with raw egg: Sixty-minute- compared with 30-minute dosing interval. Clin Exp Allergy. 2022 Sep;52(9):1114-1117. doi: 10.1111/cea.14187. Epub 2022 Jul 4. No abstract available. PMID 35719001
- Petersen BT, Gradman J. Prospective study of 5-day challenge with penicillins in children. BMJ Paediatr Open. 2020 Aug 4;4(1):e000734. doi: 10.1136/bmjpo-2020-000734. eCollection 2020. PMID 32818157
Identifiers
NCT: NCT04331522 · HCA-AP