Recruiting NCT04255264
Adipose Inflammation and Diabetes (FAB)
For patients and families
In plain language
An automatic summary of structured registry data. It is an orientation aid, not a substitute for the official protocol or a physician assessment.
- What is being studied
- This is an observational study: the protocol does not assign a study treatment.
- Who it may be relevant to
- Registry conditions: Obese. Basic parameters: 18 years — 60 years · All.
- What needs checking
- Age, condition and sex are only basic indicators. Prior treatment, laboratory values and other mandatory requirements appear in the eligibility criteria below.
- Where it takes place
- Sweden
- Next step
- Save the trial, show it to the treating physician, and confirm current recruitment with the study center. Costs, documents and travel →
Unsure about the terms? Read our patient guide →
Official title
Adipose Tissue Inflammation and Diabetes Development (Fettvävsinflammation Och Diabetesutveckling)
Overview
The study investigates whether the addition of resolution molecules can inhibit inflammation and insulin resistance in human tissue taken from obese individuals, and whether the results of these studies correlate with patient-specific resolution phenotypes.
Primary outcome measures
- Inflammatory status [Time frame: 2025]
Eligibility criteria
Inclusion criteria
- BMI 30-40 kg/m2
- Ptos (i.e. excess skin) > 3 cm
- Patient underwent gastric bypass surgery >2 years ago
- Patient has had a stable weight ≥6 months at the time of operation
- Patient does not smoke (min 6 weeks prior to surgery)
Exclusion criteria
- Patients who do not understand spoken and written Swedish
- American Society of Anesthesiologists (ASA) classification ≥ 3
- Neurological, orthopedic or rheumatologic injury or illness affecting physical ability
- Preoperatively known hernia requiring surgical operation
- Severe mental illness
Criteria are shown verbatim from the registry (in English). Final eligibility is always assessed by the study center.
Study design
- Observational model
- Cohort
Study locations
Sweden · 1 center
- Sahlgrenska university hospital — Gothenburg
Identifiers
NCT: NCT04255264 · 2019-04046